Identification of two novel <i>MVD</i> mutations and one novel <i>FDPS</i> mutation in Chinese patients with porokeratosis. [PDF]
He Y +7 more
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Metabolic engineering of endogenous MEP pathway for enhanced lycopene production in <i>Escherichia coli</i>. [PDF]
Xu X +6 more
europepmc +1 more source
Synthesis of depressin, cryptomeridiol and 4-<i>epi</i>-cryptomeridiol enabled by a terpenoid chiral pool-producing platform. [PDF]
Kong Y +8 more
europepmc +1 more source
Advances in Functional Genomics and Biotechnology for Enhancing Therapeutic Potential of Medicinal Plants. [PDF]
Zaman W, Park S.
europepmc +1 more source
From fruit to function: Squalene synthase driven triterpenoids biosynthesis in <i>Gardenia jasminoides</i> for food-active ingredient discovery. [PDF]
Wei W, Mao Y, Chen D, Guo L, Pan Y.
europepmc +1 more source
Engineering the oleaginous yeast Yarrowia lipolytica for co-production of phenolic monoterpenes thymol and carvacrol. [PDF]
Zhu J +4 more
europepmc +1 more source
Directed screening and spatial coupling of farnesyl diphosphate synthase for enhancing menaquinone-7 production in Bacillus subtilis. [PDF]
Ding X +7 more
europepmc +1 more source
A novel approach towards the synthesis of pyrophosphate analogues of farnesyl pyrophosphate
AbstractThe synthesis of two new analogues (i.e. 3 and 4) of farnesyl pyrophosphate (FPP) containing a phosphonophosphate and a phosphonophosphonate moiety was accomplished via the phosphonomorpholidate. The latter was easily obtained by treatment of a phosphonic chloride with morpholine.
Valentijn, A.R.P.M. +4 more
openaire +3 more sources
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Several phosphonate and bisphosphonate analogues of farnesyl pyrophosphate have been prepared for an examination of their ability to inhibit farnesyl protein transferase (FPTase). A Horner-Wadsworth-Emmons condensation of farnesal or geranial with tetraethyl methylenediphosphonate gave the desired vinyl phosphonates, while alkylation of the dimethyl ...
Sarah A Holstein +2 more
exaly +3 more sources

