Results 71 to 80 of about 9,308 (197)
, 2010 Binding, lateral diffusion and exchange are fundamental dynamic processes involved in protein association with cellular membranes. In this study, we developed numerical simulations of lateral diffusion and exchange of fluorophores in membranes with ...
Daniel A Beard +10 more
core +1 more source
Interfacial binding and aggregation of lamin A tail domains associated with Hutchinson–Gilford progeria syndrome [PDF]
, 2014 Hutchinson–Gilford progeria syndrome is a premature aging disorder associated with the expression of ∆50 lamin A (∆50LA), a mutant form of the nuclear structural protein lamin A (LA).
Buehler, Markus J +6 more
core +1 more source
Competition between binding partners of yeast Pex3 affects peroxisome biology
The FEBS Journal, Volume 293, Issue 1, Page 175-195, January 2026.Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange +5 more
wiley +1 more source
Apoptosis induced by clofibrate in Yoshida AH-130 hepatoma cells
Journal of Lipid Research, 2003 Clofibrate is a hypolipidemic drug belonging to the peroxisome proliferator (42) family. PPs are well-recognized hepatocarcinogens, though only for rodents and not for humans.
Rosa A. Canuto +8 more
doaj +1 more source
Journal of Lipid Research, 2005 Prelamin A undergoes multistep processing to yield lamin A, a structural protein of the nuclear lamina. Prelamin A terminates with a CAAX motif, which triggers farnesylation of a C-terminal cysteine (the C of the CAAX motif), endoproteolytic release of ...
Stephen G. Young +2 more
doaj +1 more source
A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans. [PDF]
PLoS ONE, 2016 Genetic pathways that regulate nascent neurite formation play a critical role in neuronal morphogenesis. The core planar cell polarity components VANG-1/Van Gogh and PRKL-1/Prickle are involved in blocking inappropriate neurite formation in a subset of ...
David Carr +7 more
doaj +1 more source
Complex Systems Analysis of Cell Cycling Models in Carcinogenesis [PDF]
, 2011 A new approach to the modular, complex systems analysis of nonlinear dynamics in cell cycling network transformations involved in carcinogenesis is proposed.
I. C. Baianu
core +1 more source
The role of lipid post-translational modification in plant developmental processes
Frontiers in Plant Science, 2014 Most eukaryotic proteins are post-translationally modified, and modification has profound effects on protein function. One key modification is the attachment of a lipid group to certain amino acids; this typically facilitates subcellular targeting ...
Mark Paul Running
doaj +1 more source
USP45 and Spindly are part of the same complex implicated in cell migration [PDF]
, 2018 Ubiquitylation is a protein modification implicated in several cellular processes. This process is reversible by the action of deubiquinating enzymes (DUBs).
Conte, Claudia +3 more
core +2 more sources
Aging and Cancer, Volume 6, Issue 4, Page 93-105, December 2025.Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang +17 more
wiley +1 more source