Results 71 to 80 of about 6,054 (206)
Updates on protein-prenylation and associated inherited retinopathies
Frontiers in OphthalmologyMembrane-anchored proteins play critical roles in cell signaling, cellular architecture, and membrane biology. Hydrophilic proteins are post-translationally modified by a diverse range of lipid molecules such as phospholipids ...
Sudhat Ashok +3 more
doaj +1 more source
Development of Farnesyl Transferase Inhibitors: A Review
The Oncologist, 2005 Abstract Learning Objectives After completing this course, the reader will be able to: Describe the potential mechanisms by which farnesyl transferases inhibit tumor growth.Explain possible mechanisms by which tumor cells may develop resistance to this class of agents.Discuss the scientific ...
Appels, N. +2 more
openaire +3 more sources
JCSM Communications, Volume 9, Issue 1, January/June 2026.ABSTRACT Background Muscular dystrophies (MD) are a genetically diverse group of muscle disorders, many of which arise from mutations in genes encoding components of the sarcolemma dystrophin‐associated glycoprotein complex (DGC). Despite their notorious heterogeneity, MDs consistently lead to chronic myofiber weakening, necrosis and loss of muscle ...
Yejin Kang, Pascal Bernatchez
wiley +1 more source
, 2016 Protein farnesylation is a post-translational modification involving the addition of a 15-carbon farnesyl isoprenoid to the carboxy terminus of select proteins.
Liang, Siyu Jr
core +1 more source
Reversible Binding and Trafficking of DNA Origami Between Lipid Membrane Phases
Small Structures, Volume 7, Issue 1, January 2026.A DNA origami nanostructure was functionalized with different lipophilic anchor types. Depending on the anchor type, these nanodevices selectively bind to a certain lipid phase with distinctive rigidities. Using the strand displacement method, these functionalized DNA origami nanostructures go through dimerization/monomerization steps, thereby ...
Rayehe Mamaghaniyeh, Henri G. Franquelim
wiley +1 more source
YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice
Cell Proliferation, Volume 59, Issue 1, January 2026.Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen +8 more
wiley +1 more source
Farnesylation mediates brassinosteroid biosynthesis to regulate abscisic acid responses
, 2016 Protein farnesylation is a post-translational modification involving the addition of a 15-carbon farnesyl isoprenoid to the carboxy terminus of select proteins1–3.
Liang, S (15642131) +7 more
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Frontiers in Cellular and Infection Microbiology, 2010 Microbial pathogens have evolved exquisite mechanisms to interfere and intercept host biological processes, often through molecular mimicry of specific host proteins.
Yousef eAbu Kwaik, Christopher T. Price
doaj +1 more source
Competition between binding partners of yeast Pex3 affects peroxisome biology
The FEBS Journal, Volume 293, Issue 1, Page 175-195, January 2026.Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange +5 more
wiley +1 more source
Farnesylation-dependent regulation of transcripts by PARP13
, 2015 Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2015.Cataloged from PDF version of thesis.Includes bibliographical references.PARP1 3 is a RNA-binding and catalytically inactive member of the poly(ADPribose) (PARP) family ...
Uchima, Lilen
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