Results 91 to 100 of about 184,173 (204)

Therapeutic Effect of Crocin on the NASH Model by Targeting the Fas Receptor Signaling Pathway. [PDF]

Turk J Gastroenterol, 2022
Mard SA, Savari F, Rezaie A, Khosravi M.
europepmc   +1 more source

Autoimmune lymphoproliferative syndrome in pregnancy: a case of favorable mother - fetal outcome in a well-controlled disease [PDF]

, 2014
The autoimmune lymphoproliferative syndrome(ALPS)is a disorder of abnormal lymphocyte survival caused by the dysregulation of theFasapoptotic pathway. The Fas geneis expressed at the maternal–fetal interface and is involved in the regulation of immune ...
Baek, Bleesing, Canale, Ciarmela, Correia-da-Silvia, Ferguson, Fuks, Hansford, Jerzak, Kwak-Kim, Lev, Oliveira, Rao, Rogers, Worth   +14 more
core   +1 more source

Loss of Fas Receptor Function Preserves Photoreceptor Structure and Function in Two Mouse Models of Inherited Retinal Degeneration. [PDF]

Invest Ophthalmol Vis Sci, 2022
Yao J, Wang T, Jia L, Qiu Y, Zacks DN.
europepmc   +1 more source

Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice [PDF]

, 2016
Cell death by apoptosis has a critical role during embryonic development and in maintaining tissue homeostasis. In mammals, there are two converging apoptosis pathways: the ‘extrinsic’ pathway, which is triggered by engagement of cell surface ‘death ...
A Egle, A Enders, A Strasser, A Strasser, A Strasser, A Strasser, A Strasser, A Strasser, A Villunger, AE Weant, AR Delbridge, BA Croker, Cassandra J Vandenberg, DA Hildeman, DA Steimer, E Lagasse, E Schneider, EA Reap, EM Carrington, F Rieux-Laucat, GH Fisher, I Dzhagalov St, I Vikstrom, IN Lavrik, J Hutcheson, J Opferman, JI Fletcher, JJ Weening, JM Brouwer, JT Opferman, K Fecho, K Iwai, K Nakayama, KA Fortner, KD Mason, Kirsteen J Campbell, KJ Campbell, KL O'Neill, L Chen, Lorraine A O’Reilly, M Pellegrini, MN Martina, Natasha S Anstee, P Bouillet, P Hughes, PD Hughes, PE Czabotar, PE Czabotar, Peter D Hughes, PH Krammer, PL Cohen, R Watanabe-Fukunaga, RM Perciavalle, S Cory, S Ogilvy, SF Fischer, SN Willis, SN Willis, Suzanne Cory, T Kuwana, T Moldoveanu, TH Price, TJ McDonnell, V Peperzak, WC Liles, WF Davidson   +65 more
core   +3 more sources

Different methods of detaching adherent cells and their effects on the cell surface expression of Fas receptor and Fas ligand. [PDF]

Sci Rep, 2022
Lai TY, Cao J, Ou-Yang P, Tsai CY, Lin CW, Chen CC, Tsai MK, Lee CY.   +7 more
europepmc   +1 more source

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Toll-Like Receptor 3 Signaling Induces Chronic Pancreatitis through the Fas/Fas Ligand-Mediated Cytotoxicity

The Tohoku Journal of Experimental Medicine, 2009
Innate immunity plays important roles in host defense against pathogens, but may also contribute to the development of autoimmune diseases under certain conditions. Toll-like receptors (TLRs) recognize various pathogens and induce innate immunity.
Yoshiko, Soga, Hiroaki, Komori, Tatsuhiko, Miyazaki, Norimasa, Arita, Miho, Terada, Kazuo, Kamada, Yuki, Tanaka, Takahiro, Fujino, Yoichi, Hiasa, Bunzo, Matsuura, Morikazu, Onji, Masato, Nose   +11 more
openaire   +3 more sources

Fas-independent T-cell apoptosis by dendritic cells controls autoimmune arthritis in MRL/lpr mice.

PLoS ONE, 2012
BackgroundAlthough autoimmunity in MRL/lpr mice occurs due to a defect in Fas-mediated cell death of T cells, the role of Fas-independent apoptosis in pathogenesis has rarely been investigated. We have recently reported that receptor activator of nuclear
Takashi Izawa, Tomoyuki Kondo, Mie Kurosawa, Ritsuko Oura, Kazuma Matsumoto, Eiji Tanaka, Akiko Yamada, Rieko Arakaki, Yasusei Kudo, Yoshio Hayashi, Naozumi Ishimaru   +10 more
doaj   +1 more source

Age-related changes of apoptotic cell death in human lymphocytes [PDF]

, 2006
Apoptosis seems to be involved in immunosenescence associated with aging. Moreover, in lymphocytes (PBL) of patients with Alzheimer's disease, an increased susceptibility to the apoptotic pathway has been described possibly due to impaired protection of ...
Eckert, Anne, Leutner, Silke, Müller, Walter E., Schindowski, Katharina   +3 more
core  

Expression of Fas and FasL in Trophoblastic Tissue of Women with Spontaneous and Induced Abortion Using insitu Hybridization Technique

The Iraqi Journal of Medical Sciences, 2016
Background:Apoptosis of trophoblastic cells may play a role in the pathogenesis of abortion, and one mechanism of apoptosis is Fas receptor and legand system.
Mohammed R Ali, Abdul-Razzak H Ahmed
doaj   +4 more sources