Results 101 to 110 of about 105,192 (298)
Frontiers in Endocrinology, 2014 The beneficial roles of omega-3 fatty acids (ω3-FAs) on obesity, type 2 diabetes, and other metabolic diseases are well known. Most of these effects can be explained by their anti-inflammatory effects, triggered through their receptor, G protein-coupled ...
Da Young eOh, Evelyn eWalenta
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
, 2007 Ab binding to CD20 has been shown to induce apoptosis in B cells. In this study, we demonstrate that rituximab sensitizes lymphoma B cells to Fas-induced apoptosis in a caspase-8-dependent manner. To elucidate the mechanism by which Rituximab affects Fas-
Dondorff, Monica +10 more
core +2 more sources
Therapeutic Effect of Crocin on the NASH Model by Targeting the Fas Receptor Signaling Pathway. [PDF]
Turk J Gastroenterol, 2022 Mard SA, Savari F, Rezaie A, Khosravi M.
europepmc +1 more source
, 2010 Cell-mediated xenograft rejection, including NK cells and CD8+ CTL, is a major obstacle in successful pig-to-human xenotransplantation. Human CD8+ CTL and NK cells display high cytotoxicity for pig cells, mediated at least in part by the Fas/FasL pathway.
Kwang Wook Park +9 more
core
T cells, the Next Big Target in Axial Spondyloarthritis?
Arthritis &Rheumatology, EarlyView.Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley +1 more source
Loss of Fas Receptor Function Preserves Photoreceptor Structure and Function in Two Mouse Models of Inherited Retinal Degeneration. [PDF]
Invest Ophthalmol Vis Sci, 2022 Yao J, Wang T, Jia L, Qiu Y, Zacks DN.
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
The Iraqi Journal of Medical Sciences, 2016 Background:Apoptosis of trophoblastic cells may play a role in the pathogenesis of abortion, and one mechanism of apoptosis is Fas receptor and legand system.
Mohammed R Ali, Abdul-Razzak H Ahmed
doaj +6 more sources
Different methods of detaching adherent cells and their effects on the cell surface expression of Fas receptor and Fas ligand. [PDF]
Sci Rep, 2022 Lai TY +7 more
europepmc +1 more source