Results 121 to 130 of about 105,192 (298)

Empowering Circular Startups: Unveiling the Blueprint for Circular Business Models

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular startups are increasingly recognized as key drivers in the transition toward a circular economy. Yet the business models (BMs) through which these startups operationalize circularity remain poorly understood, limiting the ability of entrepreneurial ecosystem actors to offer effective support.
Ann‐Sophie Finner, Linda Sagnier Eckert, Orestis Terzidis   +2 more
wiley   +1 more source

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

Clinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Gentamicin-induced hair cell death is not dependent on the apoptosis receptor Fas

, 2003
OBJECTIVES/HYPOTHESIS: The hair cells are the most vulnerable elements in the cochlea, and damage to them is the most common cause of sensorineural hearing loss.
Bodmer, Daniel, Ryan, Allen F., Pak, Kwang, Pak, K, Bodmer, D, Brors, D, Ryan, A F, Brors, Dominik, Bodmer, M, Bodmer, Morana   +9 more
core   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Short-Term versus Long-Term Intermittent Hypobaric Hypoxia on Cardiac fibrosis and Fas-Death-Receptor Dependent Apoptotic Pathway in Rat Hearts.

, 2012
[[abstract]]It is unknown if short-term and long-term intermittent hypobaric hypoxic challenges both exert pro-apoptotic effects on Fas death receptor-dependent apoptotic pathway in rat hearts.
Yueh-Min Lin;Shu-Kuei Huang;Hsueh Fang Wang;Li-Mien Chen;Fuu-Jen Tsai;Hsi-Hsien Hsu;Chia-Hua Kuo;Paulus S. Wang;Chih-Yang Huang;Shin-Da Lee
core   +1 more source

Apoptosis-related factors (Fas receptor, Fas ligand, FADD) in early tooth development of the field vole (Microtus agrestis)

, 2005
Fas (CD95/APO-1) belongs to the TNF receptor (TNFR) family. Fas ligand binding followed by Fas-receptor oligomerisation leads to formation of a death-inducing signal complex starting with recruitment of the Fas-adapter protein (FADD).
Tucker, A S; id_orcid, Matalova, E, Misek, I   +2 more
core   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Tick‐Tock, the Time Has Come: Leveraging TikTok to Understand, Prevent, and Treat Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective TikTok—a highly engaging social media platform with a powerful algorithm that displays short videos—has become massively popular in recent years. As research highlights the concerning relationship between image‐based content on social media and disordered eating symptoms, TikTok may serve as an optimal platform to understand eating ...
Macarena Kruger, Isabella Pruscino, Caroline G. Martin, Elizabeth A. Velkoff   +3 more
wiley   +1 more source

PRO-APOPTOTIC EFFECTS OF APPLE PROCYANIDINS IN HUMAN COLON CANCER CELLS AND THEIR DERIVED METASTATIC CELLS EFECTO PRO-APOPTÓTICO DE PROCIANIDINAS DE MANZANA EN CÉLULAS HUMANAS DE CÁNCER DE COLON Y SUS CÉLULAS METASTÁSICAS DERIVADAS

Vitae, 2010
Apples are a rich source of Procyanidins (Pcy) which are able to inhibit colon carcinogenesis in animal models, but the mechanisms through which this occurs are not well understood.The evidence obtained in our laboratory and by other researchers, which ...
María E MALDONADO C, Francis RAUL
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