Longitudinal Immune Profiling of T Cell Exhaustion During IL-17A Blockade in a Patient With HLA-B27-negative Spondyloarthritis and Sjögren's Syndrome: A Case Report. [PDF]
Su YS +6 more
europepmc +1 more source
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma +14 more
wiley +1 more source
Association of soluble apoptotic biomarkers (FAS,TNFR1 and TRAIL-R2) with β-cell dysfunction in early glucose dysregulation. [PDF]
Ayash R, Kabalan Y, Chamaa S.
europepmc +1 more source
Patient‐Reported Communication Decline Following Deep Brain Stimulation in Parkinson's Disease
Abstract Background Objective decline in communication abilities following Deep Brain Stimulation (DBS) in People with Parkinson's disease (PwP) is common; however, patient perspectives remain under‐investigated. Objectives This study examined subjective change in communicative efficacy using the Communicative Participation Item Bank (CPIB) in PwP ...
Stephanie M. Simone +2 more
wiley +1 more source
Cannabidiol sensitizes triple-negative breast cancer cells to NK cell-mediated killing via EGFR inhibition and FAS upregulation. [PDF]
Garunyapakun P +5 more
europepmc +1 more source
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
The role of fatty acids in neurodegenerative diseases: mechanistic insights and therapeutic strategies. [PDF]
Yang Y +7 more
europepmc +1 more source
Abstract Objective Investigate the efficacy of immediate‐release (IR) amantadine in reducing the risk of peak‐dose dyskinesia in early Parkinson's disease (PD) as add‐on to levodopa. Background While the use of amantadine to manage dyskinesia in PD is well supported by controlled clinical trials, data on its efficacy in patients without motor ...
Olivier Rascol +106 more
wiley +1 more source
Increased Tumor Necrosis Factor Superfamily Members in Neuroinflammatory Schizophrenia and Bipolar Disorder Midbrains. [PDF]
Mendez-Victoriano G +16 more
europepmc +1 more source

