Results 41 to 50 of about 190,947 (267)

Observation of bi-directional global Alfvén eigenmodes in the MAST-U tokamak

Nuclear Fusion
The first observations and classification of deuterium beam-driven sub-cyclotron frequency range Alfvén eigenmodes (AEs) are presented for the MAST-Upgrade tokamak. Sets of observed eigenmodes are separated in frequency by approximately 200 kHz.
M.B. Dreval, H.J.C. Oliver, S.E. Sharapov, J.F. Rivero-Rodriguez, M. Fitzgerald, C. Michael, R. Ochoukov, L. Velarde, M. Cecconello, D. Ryan, the MAST-U Team   +10 more
doaj   +1 more source

4D and 5D phase-space tomography using slowing-down physics regularization

Nuclear Fusion, 2023
We compute reconstructions of 4D and 5D fast-ion phase-space distribution functions in fusion plasmas from synthetic projections of these functions. The fast-ion phase-space distribution functions originating from neutral beam injection (NBI) at TCV and ...
B.S. Schmidt, M. Salewski, D. Moseev, M. Baquero-Ruiz, P.C. Hansen, J. Eriksson, O. Ford, G. Gorini, H. Järleblad, Ye O. Kazakov, D. Kulla, S. Lazerson, J.E. Mencke, D. Mykytchuk, M. Nocente, P. Poloskei, M. Rud, A. Snicker, L. Stagner, S. Äkäslompolo, the W7-X Team   +20 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Preliminary study of velocity-space distribution of fast-ion loss under ion cyclotron resonance heating in the EAST

He jishu, 2023
BackgroundScintillator-based fast-ion loss detector (FILD) can measure the velocity-space distribution of fast-ion loss and are key in studying the control mechanism of fast-ion loss in nuclear fusion devices.PurposeThis study aims to obtain the velocity-
WANG Shusong, HUANG Juan, CHANG Jiafeng, ZHANG Xinjun, GAO Wei, FU Jing, SUN Yanxu, SHI Chang, WANG Xihui, ZHANG Zixin   +9 more
doaj   +1 more source

Calibration techniques for fast-ion Dα diagnostics [PDF]

Review of Scientific Instruments, 2012
Fast-ion Dα measurements are an application of visible charge-exchange recombination (CER) spectroscopy that provide information about the energetic ion population. Like other CER diagnostics, the standard intensity calibration is obtained with an integrating sphere during a vacuum vessel opening.
Heidbrink, WW, Bortolon, A, Muscatello, CM, Ruskov, E, Grierson, BA, Podestá, M   +5 more
openaire   +4 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Optimization of the operational domain for ICRH scenarios in WEST from statistical analysis

Nuclear Fusion, 2023
In the WEST tokamak, the Ion Cyclotron Resonance Heating (ICRH) system plays a substantial role in increasing the plasma temperature. However, its efficiency can be lowered by two main phenomena: ripple-induced fast ion losses and technical limits on the
D. Moiraf, J. Morales, L. Colas, N. Fedorczak, J. Gaspar, R. Dumont, the WEST Team   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling of heat flux on the main limiter in EAST

Nuclear Fusion
Heat flux on plasma-facing components is one of the key issues in tokamak operation. In EAST, severe damages occurred on the main limiters due to high heat loads limit high-power and long-pulse operation in recent campaigns.
Binfu Gao, Dahuan Zhu, Rui Ding, Chuannan Xuan, Bin Zhang, Rong Yan, Mehdi Firdaouss, Shaocheng Liu, Yang Wang, Zongxiao Guo, Chunyu He, Wenxue Fu, Baoguo Wang, Junling Chen, the EAST team   +14 more
doaj   +1 more source