Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
: This study investigated the effects of varying fat levels and ratios of coconut to palm fat in milk replacer on solid feed intake and performance of male Holstein calves fed a high milk replacer allowance.
J.V.R. Lovatti +5 more
doaj +1 more source
INULIN AS A PREBIOTIC AND FAT REPLACER IN MEAT PRODUCTS [PDF]
Fat reduction in meat products is demanded by consumers concerninghealth issues but represents a serious challenge for meat industry as fatty tissue plays an important role for the products properties.
Vasilev, Dragan +13 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Effect of feeding liquid milk supplement on litter performances and on sow back-fat thickness change during the suckling period [PDF]
The aim of the present study was to investigate the effect of liquid milk supplement on litter performance (weight development of the piglets, weaning weight and mortality) and on sow back-fat thickness change during the suckling period.
G. Novotni-Dankó +3 more
doaj +1 more source
Quality characteristics and oxidative stabilityof chicken kavurma formulated with chicken abdominal fat as beef fat replacer [PDF]
Kavurma is a traditional cooked ready-to-eat meat product that mainly produce in Middle East countries. In kavurma formulation, main ingredients are beef/mutton meat, beef/mutton fat and salt.
Özer, M +5 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Pengaruh egg replacer terhadap karakteristik egg-free mayonnaise probiotik
Mayonnaise is an oil in water (O/W) semi-solid emulsion that is widely used in the food industry as salad dressing, sauce, and condiment. The use of eggs in the production of mayonnaise was considered health concerns for some people.
Novia Hidayati Inasa +3 more
doaj +1 more source
EFFECT OF USING ARTICHOKE AS A SOURCE OF INULIN ON LOW CALORIE ICE CREAM QUALITY [PDF]
The effect of artichoke as a source of inulin which is used as a fat replacer on physic-chemical characteristics and sensory attributes of ice cream with different level of fat (12, 9, and 6%) with 11% SNF were investigated.
W. Nasr +2 more
doaj +1 more source
Efeitos da inulina nas propriedades físicas, químicas, de textura e aceitabilidade no desenvolvimento de muffin destinado a consumidores em idade escolar [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-graduação em Ciência dos alimentos, Florianópolis, 2013A obesidade infantil já é epidemia; o problema é global e se estende por todo o mundo ...
Kuntz, Marilyn Gonçalves Ferreira
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