Results 61 to 70 of about 13,309 (356)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Early weaning of calves after different dietary regimens affects later rumen development, growth, and carcass traits in Hanwoo cattle [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective The main objective of this study was to determine the effect of different diets for early-weaned (EW) calves on rumen development, and how this affects fat deposition in the longissimus dorsi of adult Korean Hanwoo beef cattle. Methods Three EW
Kondreddy Eswar Reddy   +9 more
doaj   +1 more source

Effect of Enterococcus faecium SF68 on growth performance and in vivo digestibility in buffalo calves [PDF]

open access: yes, 2007
The effect of dietary supplementation with Enterococcus faecium strain SF68 on growth performance, faecal consistency and in vivo digestibility in buffalo (Bubalus bubalis) calves was evaluated.
BILANCIONE, ANTONIO   +4 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effects of fat content of high-protein milk replacer on intake and growth performance of Holstein calves in summer and winter

open access: yesJournal of Dairy Science
: The objective of this study was to evaluate the effects of fat content of high-protein milk replacer on intake and growth performance of dairy calves in summer and winter. Eighty-four Holstein heifer calves (BW at 7 d of age, 42.2 ± 2.54 kg; mean ± SD)
R. Fukami   +4 more
doaj   +1 more source

Evaluation of tilapia fish burgers as affected by different replacement levels of mashed pumpkin or mashed potato

open access: yesJournal of the Saudi Society of Agricultural Sciences, 2019
Mashed pumpkin or mashed potato was used in the tilapia fish burger formulation. The proximate composition, cooking characteristics, chemical quality, color, texture and sensory properties of tilapia fish burgers were evaluated.
Hala A. Ali   +3 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Effects of energy source on growth and body composition of Holstein calves fed only milk replacer or whole milk

open access: yesJournal of Dairy Science
: Whether lactose or fat is a better fuel for protein synthesis and deposition in young calves has remained controversial. Also, it remains uncertain whether bioactive factors in whole milk might influence growth compared with a milk replacer of similar ...
K.S. Bartlett   +6 more
doaj   +1 more source

Effect of milk replacer and rumen inert fat on growth and reproduction of Malpura ram lambs

open access: yesAnimal, 2014
The objective of this study was to assess the effects of milk replacer and rumen inert fat on growth, testicular development, puberty, semen production and sperm motion characteristics of ram lambs reared under intensive management in semi-arid climatic ...
D. Kumar   +3 more
doaj   +1 more source

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