Results 61 to 70 of about 11,554 (286)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Influence of Partial Fat Replacement With Lecithin on the Product Characteristics of a Special Hungarian Cold Cut [PDF]

, 2016
Replacement of animal fat with plant oils is a very popular research field, due to the increasing prevalence of cardiovascular diseases in association with saturated fatty acid consumption.
Belovai, J., Bánáti, D., Fébel, H., Mézes, M., Romvári, R., Szabó, A.   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Effects of fat content of high-protein milk replacer on intake and growth performance of Holstein calves in summer and winter

Journal of Dairy Science
: The objective of this study was to evaluate the effects of fat content of high-protein milk replacer on intake and growth performance of dairy calves in summer and winter. Eighty-four Holstein heifer calves (BW at 7 d of age, 42.2 ± 2.54 kg; mean ± SD)
R. Fukami, N. Kobayashi, K. Murayama, M. Oba, T. Sugino   +4 more
doaj   +1 more source

Evaluation of tilapia fish burgers as affected by different replacement levels of mashed pumpkin or mashed potato

Journal of the Saudi Society of Agricultural Sciences, 2019
Mashed pumpkin or mashed potato was used in the tilapia fish burger formulation. The proximate composition, cooking characteristics, chemical quality, color, texture and sensory properties of tilapia fish burgers were evaluated.
Hala A. Ali, Esam H. Mansour, Abo El-Fath A. E-lBedawey, Atef S. Osheba   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Determination of Quality Characteristic of Biscuits Including Ground Yellow Poppy Seed as Fat Replacer

International Journal of Secondary Metabolite, 2017
In this study, fat was replaced by ground yellow poppy seed in biscuit formulation for producing low fat biscuit and the changes in physical characteristics, color values and total phenolic content of biscuits with fat replacement were investigated.
Seda Yalcin
doaj   +1 more source

A pilot socio-economic analysis of QLIF dairy projects [PDF]

, 2008
A pilot socio-economic impact assessment was carried out on three dairy projects within QLIF to identify the business, consumer and policy issues likely to influence the adoption of the innovations resulting from QLIF.
Butler, Dr. Gillian, Klocke, Peter, Lampkin, Dr. Nicolas, Leifert, Prof. Carlo, Nicholas, Dr. Phillipa, Wagenaar, J.P.T.M.   +5 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effects of energy source on growth and body composition of Holstein calves fed only milk replacer or whole milk

Journal of Dairy Science
: Whether lactose or fat is a better fuel for protein synthesis and deposition in young calves has remained controversial. Also, it remains uncertain whether bioactive factors in whole milk might influence growth compared with a milk replacer of similar ...
K.S. Bartlett, F.K. McKeith, R.A. Molano, M.E. Van Amburgh, M.J. VandeHaar, G.E. Dahl, J.K. Drackley   +6 more
doaj   +1 more source