Results 21 to 30 of about 6,179,891 (361)

Reprogramming of fatty acid metabolism in cancer

British Journal of Cancer, 2019
A common feature of cancer cells is their ability to rewire their metabolism to sustain the production of ATP and macromolecules needed for cell growth, division and survival.
Nikos Koundouros, G. Poulogiannis
semanticscholar   +1 more source

Fatty Acid Signaling Mechanisms in Neural Cells: Fatty Acid Receptors

Frontiers in Cellular Neuroscience, 2019
Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be stored as triglycerides, degraded by β-oxidation or used in phospholipids’ synthesis, the main components of biological membranes. It has been shown that these
Lisandro Jorge Falomir-Lockhart, Lisandro Jorge Falomir-Lockhart, Gian Franco Cavazzutti, Gian Franco Cavazzutti, Ezequiel Giménez, Ezequiel Giménez, Andrés Martín Toscani, Andrés Martín Toscani   +7 more
doaj   +1 more source

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations[S]

Journal of Lipid Research, 2017
MUFAs are unsaturated FAs with one double bond and are derived from endogenous synthesis and dietary intake. Accumulating evidence has suggested that plasma and erythrocyte MUFA levels are associated with cardiometabolic disorders, including CVD, T2D ...
Yao Hu, Toshiko Tanaka, Jingwen Zhu, Weihua Guan, Jason H.Y. Wu, Bruce M. Psaty, Barbara McKnight, Irena B. King, Qi Sun, Melissa Richard, Ani Manichaikul, Alexis C. Frazier-Wood, Edmond K. Kabagambe, Paul N. Hopkins, Jose M. Ordovas, Luigi Ferrucci, Stefania Bandinelli, Donna K. Arnett, Yii-Der I. Chen, Shuang Liang, David S. Siscovick, Michael Y. Tsai, Stephen S. Rich, Myriam Fornage, Frank B. Hu, Eric B. Rimm, Majken K. Jensen, Rozenn N. Lemaitre, Dariush Mozaffarian, Lyn M. Steffen, Andrew P. Morris, Huaixing Li, Xu Lin   +32 more
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Amino Acid and Fatty Acid Compositions of Sea Cucumber Stichopus Vastus from Salemo Island Waters, Indonesia

Squalen, 2018
Coastal waters of Indonesia have considerable biodiversity of sea cucumbers. In the present study the amino acid and fatty acid contents in sea cucumber Stichopus vastus collected from Salemo Island waters Indonesia were determined.
Abdullah Rasyid
doaj   +1 more source

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Nature, 2019
Most tumours have an aberrantly activated lipid metabolism1,2 that enables them to synthesize, elongate and desaturate fatty acids to support proliferation.
K. Vriens, Stefan Christe, S. Parik, D. Broekaert, Kazuaki Yoshinaga, A. Talebi, J. Dehairs, Carmen Escalona-Noguero, Robert Schmieder, T. Cornfield, C. Charlton, L. Romero-Pérez, Matteo Rossi, Gianmarco Rinaldi, M. Orth, R. Boon, Axelle Kerstens, Suet-Ying Kwan, B. Faubert, Andrés Méndez-Lucas, C. Kopitz, Ting Chen, J. Fernández-García, Joao A. G. Duarte, A. Schmitz, Patrick Steigemann, M. Najimi, Andreas Hägebarth, J. V. Van Ginderachter, E. Sokal, N. Gotoh, Kwok-kin Wong, C. Verfaillie, R. Derua, S. Munck, M. Yuneva, L. Beretta, R. Deberardinis, J. Swinnen, L. Hodson, D. Cassiman, C. Verslype, Sven Christian, S. Grünewald, T. Grünewald, S. Fendt   +45 more
semanticscholar   +1 more source

Associations Between Plasma Omega‐3 and Fish Oil Use With Risk of Atrial Fibrillation in the UK Biobank

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Meta‐analyses of randomized trials with omega‐3 products found an increased risk of atrial fibrillation (AF), and a recent study from the UK Biobank concluded that fish oil supplement (FOS) use was likewise associated with increased risk of AF.
Evan O’Keefe, James H. O’Keefe, Nathan L. Tintle, W. G. Franco, Jason Westra, William S. Harris   +5 more
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Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling

Cell Reports, 2018
Summary: It is well understood that fatty acids can be synthesized, imported, and modified to meet requisite demands in cells. However, following the movement of fatty acids through the multiplicity of these metabolic steps has remained difficult.
Joseph P. Argus, Moses Q. Wilks, Quan D. Zhou, Wei Yuan Hsieh, Elvira Khialeeva, Xen Ping Hoi, Viet Bui, Shili Xu, Amy K. Yu, Eric S. Wang, Harvey R. Herschman, Kevin J. Williams, Steven J. Bensinger   +12 more
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The Effects of Omega-3 Supplementation on the Omega-3 Index and Quality of Life and Pain Scores in Dogs

Animals
This study in dogs had two objectives: first, to determine whether a daily supplement of marine omega-3 (EPA and DHA) would (1) increase red blood cell EPA + DHA levels (i.e., the Omega-3 Index derived from dried blood spot analysis) and (2) impact ...
Carolina Carlisle, Brandon T. Metzger, Nathan L. Tintle, Kristine Polley, Kristina H. Jackson, Sara Le Brun-Blashka, Jody Griffiths, William S. Harris   +7 more
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Polyunsaturated fatty acid accumulation in the lipids of cultured fibroblasts and smooth muscle cells

Journal of Lipid Research, 1981
The lipid content per cell of cells in tissue culture depended on the cell type. Fibroblasts derived from human neonatal foreskin contained less triglyceride and phospholipid and more cholesteryl ester than smooth muscle cells derived from guinea pig ...
V C Gavino, J S Miller, J M Dillman, G E Milo, D G Cornwell   +4 more
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Release of free fatty acids from Ehrlich ascites tumor cells

Journal of Lipid Research, 1966
Ehrlich ascites tumor cells release free fatty acids (FFA) during in vitro incubation in media that contain albumin. The released FFA are derived by lipolysis from endogenous lipid esters.
Arthur A. Spector, Daniel Steinberg
doaj   +1 more source