Results 21 to 30 of about 5,949,005 (346)
TLR4 links innate immunity and fatty acid-induced insulin resistance.
Journal of Clinical Investigation, 2006 TLR4 is the receptor for LPS and plays a critical role in innate immunity. Stimulation of TLR4 activates proinflammatory pathways and induces cytokine expression in a variety of cell types.
Hang Shi +5 more
semanticscholar +1 more source
Fatty Acid Signaling Mechanisms in Neural Cells: Fatty Acid Receptors
Frontiers in Cellular Neuroscience, 2019 Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be stored as triglycerides, degraded by β-oxidation or used in phospholipids’ synthesis, the main components of biological membranes. It has been shown that these
Lisandro Jorge Falomir-Lockhart +7 more
doaj +1 more source
Squalen, 2018 Coastal waters of Indonesia have considerable biodiversity of sea cucumbers. In the present study the amino acid and fatty acid contents in sea cucumber Stichopus vastus collected from Salemo Island waters Indonesia were determined.
Abdullah Rasyid
doaj +1 more source
Reprogramming of fatty acid metabolism in cancer
British Journal of Cancer, 2019 A common feature of cancer cells is their ability to rewire their metabolism to sustain the production of ATP and macromolecules needed for cell growth, division and survival.
Nikos Koundouros, G. Poulogiannis
semanticscholar +1 more source
Journal of Lipid Research, 1974 The partition ratios of radioactive fatty acids between n-heptane and a physiological buffer at 37 degrees C were measured. The fatty acids included the saturated acids with an even number of carbons from 10 to 18 and the unsaturated acids oleic, linoleic, and linolenic.
Richard B. Simpson +7 more
openaire +4 more sources
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Nature, 2019 Most tumours have an aberrantly activated lipid metabolism1,2 that enables them to synthesize, elongate and desaturate fatty acids to support proliferation.
K. Vriens +45 more
semanticscholar +1 more source
Current Opinion in Clinical Nutrition and Metabolic Care, 2014 The purpose of this review is to assess the findings of recent studies on the effects of fatty acids on epigenetic process and the role of epigenetics in regulating fatty acid metabolism.The DNA methylation status of the Fads2 promoter was increased in the liver of the offspring of mice fed an α-linolenic acid-enriched diet during pregnancy.
Burdge, Graham C., Lillycrop, Karen A.
openaire +6 more sources
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
Nutrients, 2016 In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large ...
A. Simopoulos
semanticscholar +1 more source
Effects of n‐3 Fatty Acid Supplements in Diabetes Mellitus
New England Journal of Medicine, 2018 BACKGROUND Increased intake of n‐3 fatty acids has been associated with a reduced risk of cardiovascular disease in observational studies, but this finding has not been confirmed in randomized trials.
L. Bowman +26 more
semanticscholar +1 more source
AnimalsThis study in dogs had two objectives: first, to determine whether a daily supplement of marine omega-3 (EPA and DHA) would (1) increase red blood cell EPA + DHA levels (i.e., the Omega-3 Index derived from dried blood spot analysis) and (2) impact ...
Carolina Carlisle +7 more
doaj +1 more source