Results 61 to 70 of about 6,179,891 (361)
Key Molecules of Fatty Acid Metabolism in Gastric Cancer
Biomolecules, 2022 Fatty acid metabolism is closely linked to the progression of gastric cancer (GC), a very aggressive and life-threatening tumor. This study examines linked molecules, such as Sterol Regulatory Element-Binding Protein 1 (SREBP1), ATP Citrate Lyase (ACLY),
Chunlei Li +4 more
doaj +1 more source
, 2016 Fatty acids are long-chain hydrocarbons. They are called unsaturated fatty acids when they lack the maximum possible number of hydrogen atoms attached to every carbon atom. For example, if stearic acid, which has 18 carbon atoms and frequently occurs in animal and plant fats, is missing 2 hydrogen atoms, then a double bond is present and the resulting ...
openaire +1 more source
Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle
Reviews in Endocrine & Metabolic Disorders, 2018 Mitochondrial fatty acid oxidation is an essential pathway for energy production, especially during prolonged fasting and sub-maximal exercise. Long-chain fatty acids are the most abundant fatty acids in the human diet and in body stores, and more than ...
Suzan J G Knottnerus +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Polyunsaturated Fatty Acids. IV.
Journal of Japan Oil Chemists' Society, 1960 Infrared absorption spectra of polyunsaturated fatty acid esters obtained from cuttle fish oils, showed a characteristic absorption at 1395cm-1, in addition to the typical absorption of normal fatty acid methylesters. This absorption at 1395cm-1 was related to the double bond, since by hydrogenation or autoxidation it was vanished away.Methyl linoleate,
Takaharu MIYAKAWA, Hideo NOMIZU
openaire +4 more sources
HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism
Nature Communications, 2017 Clear cell renal cell carcinoma (ccRCC) is histologically defined by its lipid and glycogen-rich cytoplasmic deposits. Alterations in the VHL tumor suppressor stabilizing the hypoxia-inducible factors (HIFs) are the most prevalent molecular features of ...
Weinan Du +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Apparent Digestibility of Macronutrients and Fatty Acids from Microalgae (Schizochytrium sp.) Fed to Rainbow Trout (Oncorhynchus mykiss): A Potential Candidate for Fish Oil Substitution [PDF]
, 2021 Amélie Bélanger +4 more
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Stress Hormones Cortisol and Aldosterone, and Selected Markers of Oxidative Stress in Response to Long-Term Supplementation with Omega-3 Fatty Acids in Adolescent Children with Depression [PDF]
, 2022 Henrieta Oravcová +5 more
openalex +1 more source