Results 101 to 110 of about 11,683 (171)

Synthesis and evaluation of isoquinolinyl and pyridinyl-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase to alleviate orofacial hyperalgesia in the rat. [PDF]

Biochem Biophys Rep
Carr D, Gunari S, Gorostiza G, Mercado M, Pavana L, Duong L, Gomez K, Salinas S, Garcia C, Tsang A, Morisseau C, Hammock BD, Pecic S, Kandasamy R.   +13 more
europepmc   +1 more source

Carbamates with <i>ortho</i>-Substituted <i>O</i>‑Phenyl Groups as Dual Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: Inhibitory Potency, Hydrolytic Stability, and QSAR Studies. [PDF]

ACS Med Chem Lett
Depmeier T, Hanekamp W, Lehr M.
europepmc   +1 more source

Fatty acid amide hydrolase (FAAH) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Structure-activity relationship studies and pharmacological evaluation of 4-phenylthiazoles as dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. [PDF]

Bioorg Med Chem
Yuan C, Tsang A, Berumen M, Rodriguez A, Yun F, Mesic A, Olivares A, Dubon L, Nguyen A, Pavana L, Mercado M, Gorostiza G, Morisseau C, Hammock BD, Kandasamy R, Pecic S.   +15 more
europepmc   +1 more source

4,4-Dimethylsterols Reduces Fat Accumulation via Inhibiting Fatty Acid Amide Hydrolase In Vitro and In Vivo. [PDF]

Research (Wash D C)
Zhang T, Xie L, Guo Y, Wang Z, Guo X, Liu R, Jin Q, Chang M, Wang X.   +8 more
europepmc   +1 more source

Mitigation of cisplatin-induced acute kidney injury through oral administration of fatty acid amide hydrolase inhibitor PF-04457845. [PDF]

J Pharmacol Exp Ther
Chen C, Wang W, Poklis JL, Li PL, Lichtman AH, Gewirtz DA, Li N.   +6 more
europepmc   +1 more source

Fatty acid amide hydrolase activity in the dorsal periaqueductal gray attenuates neuropathic pain and associated dysautonomia.

Am J Physiol Regul Integr Comp Physiol, 2022
Woyach V, Sherman K, Hillard CJ, Hopp FA, Hogan QH, Dean C.   +5 more
europepmc   +1 more source

The efficacy of elevating anandamide via inhibition of fatty acid amide hydrolase (FAAH) combined with internet-delivered cognitive behavioral therapy in the treatment of post-traumatic stress disorder: a randomized, placebo-controlled clinical trial. [PDF]

Neuropsychopharmacology
Mayo LM, Gauffin E, Petrie GN, Tansey R, Mazurka R, Haggarty CJ, Jones MR, Engelbrektsson H, Aminoff V, Hühne-Landgraf A, Schmidt ME, Pemberton DJ, Fredlund C, Östman L, Karlsson H, Löfberg A, Pietrzak M, Andersson G, Capusan AJ, Hill MN, Heilig M.   +20 more
europepmc   +1 more source

Efficacy and safety of JNJ-42165279, a fatty acid amide hydrolase inhibitor, in adolescents and adults with autism spectrum disorder: a randomized, phase 2, placebo-controlled study. [PDF]

Neuropsychopharmacology
Klein ME, Bangerter A, Halter RJ, Cooper K, Aguilar Z, Canuso CM, Drevets WC, Schmidt ME, Pandina G.   +8 more
europepmc   +1 more source

4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats. [PDF]

BBA Adv
Carr D, Chin C, Chacon T, Herawi MK, Gonzalez M, West R, Morisseau C, Hammock BD, Pecic S, Kandasamy R.   +9 more
europepmc   +1 more source