Results 241 to 250 of about 404,405 (316)

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Expression of the peanut diacylglycerol acyltransferase 3 increases the neutral lipid content and improves the fatty acid composition of <i>Chlorella vulgaris</i>. [PDF]

Front Plant Sci
Topf M, Andreeva A, Saul H, Tenenvorzel T, Davidi-Shwarts L, Dadon Z, Berezin I, Kinel-Tahan Y, Yehoshua Y, Shaul O.   +9 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Changes in plasma fatty acid composition in females with lipedema following low-carbohydrate vs low-fat diets and associations with pain reduction. [PDF]

Nutr J
Lundanes J, Nes VF, Hansson P, Fristedt R, Landberg R, Martins C, Nymo S.   +6 more
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Comparative Bioactivities and Fatty Acid Composition of Pinus koraiensis Leaf Oils Obtained Using Different Extraction Methods. [PDF]

Life (Basel)
Kim JE, Jang KT, An L, Lee MH, Lee HJ.
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Chemical profiling and biological activities of the medicinal macrofungus Coriolopsis gallica: volatile, non-volatile, and fatty acid composition with antioxidant and in silico-supported anti-inflammatory properties. [PDF]

Daru
Zatout R, Benslama O, Zatout C, Garzoli S.   +3 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Genetic determinism of fatty acid composition in liver, muscle, backfat and plasma and its link to immunocompetence and performance in pigs. [PDF]

Sci Rep
Hernández-Banqué C, Liu J, Jové-Juncà T, González-Rodríguez O, Portero-Otín M, Folch JM, Quintanilla R, Ballester M.   +7 more
europepmc   +1 more source