Results 151 to 160 of about 2,751,456 (226)

Extracellular Vesicle‐Encapsulated Small RNAs From Clostridium Butyricum Modulate Host Intestinal Lipid Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu, Yiwen He, Jing Liang, Qi Han, Xuqing Liang, Guangtian Cao, Yulong Tang, Liuqin He, Yulong Yin, Xihong Zhou   +9 more
wiley   +1 more source

Comprehensive analysis of fatty acid desaturase 3 in clear cell renal cell carcinoma: insights into tumor progression, immune microenvironment, and clinical outcomes. [PDF]

Front Immunol
Chen ST, Zhou DR, Ge YJ, Chang L, Guo SH, Wu GS, Feng NH.   +6 more
europepmc   +1 more source

scRNA-seq Reveals the Mechanism of Fatty Acid Desaturase 2 Mutation to Repress Leaf Growth in Peanut (Arachis hypogaea L.). [PDF]

Cells, 2023
Du P, Deng Q, Wang W, Garg V, Lu Q, Huang L, Wang R, Li H, Huai D, Chen X, Varshney RK, Hong Y, Liu H.   +12 more
europepmc   +1 more source

Organoids: Current Applications and Future Directions

MedComm, Volume 7, Issue 10, October 2026.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng, Yue Wang, Canhui Cao, Feng Deng, Weisi Lian, Xingtong Chen, Mingmei Lin, Zhonghong Zeng, Dan Mo, Shangqi Li, Yilei He, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +14 more
wiley   +1 more source

Combinations of mutations in the raffinose synthase genes and the fatty acid desaturase genes for improvement of soybean oil and meal traits. [PDF]

Mol Breed
Whitney K, Carrero-Colón M, Simsek S, Hudson K.   +3 more
europepmc   +1 more source

Genome-Wide Characterization and Expression Analysis of Fatty acid Desaturase Gene Family in Poplar. [PDF]

Int J Mol Sci, 2022
Wei H, Movahedi A, Xu S, Zhang Y, Liu G, Aghaei-Dargiri S, Ghaderi Zefrehei M, Zhu S, Yu C, Chen Y, Zhong F, Zhang J.   +11 more
europepmc   +1 more source

Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded‐Hypertensive Diabetic Db/Db Mice

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
In salt‐loaded, hypertensive diabetic db/db mice with diabetic kidney disease, dapagliflozin lowered blood pressure and reduced tubular and glomerular injury. Mechanistically, dapagliflozin increased cullin E3 ligase abundance, promoting degradation of NKCC2.
Zenab Shahzad, Niharika Bala, Arooba Illyas, Amir Kazory, Indra Chandrasekar, Abdel A. Alli   +5 more
wiley   +1 more source

Fatty acid desaturase genetic variations in heart failure and cardiovascular disease. [PDF]

Am Heart J Plus
Gittess D, Thompson I, Traktuev DO, Duarte JD, Keeley EC.   +4 more
europepmc   +1 more source

Overexpression of fatty acid desaturase 3 predicts poor prognosis in head and neck squamous cell carcinoma. [PDF]

Medicine (Baltimore), 2022
Su K, Wang Y, Gu H, Ma L, Xuan G.
europepmc   +1 more source

Lipid Accumulation Promotes Tumorigenic Behaviour of Colorectal Cancer Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Obesity and hyperlipidemia are risk factors for the development and progression of different types of cancer including colorectal cancer (CRC). The underlying mechanisms are only incompletely understood. The aim of this study was to assess the impact of hyperlipidemic conditions on tumorigenic behaviour of CRC cells and the effect of obesity ...
Tatjana Itzenhäuser, Fulya Suzan Schildt, Seraphine Jochem, Judith Sommer, Michael Stürzl, Elisabeth Naschberger, Anja Katrin Boßerhoff, Claus Hellerbrand   +7 more
wiley   +1 more source