Elongation of very long-chain (>C24) fatty acids in Clarias gariepinus: Cloning, functional characterization and tissue expression of elovl4 elongases [PDF]
, 2016 Elongation of very long-chain fatty acid 4 (Elovl4) proteins participate in the biosynthesis of very long-chain (>C24) saturated and polyunsaturated fatty acids (FA).
Navarro, Juan C +9 more
core +1 more source
Assessment of genetically modified oilseed rape LBFLFK (application EFSA‐GMO‐DE‐2019‐157)
EFSA JournalApplication EFSA‐GMO‐DE‐2019‐157 (oilseed rape LBFLFK) was submitted to EFSA to be risk assessed as full‐scope, i.e. for import, processing, and food and feed uses, within the EU.
EFSA Panel on Genetically Modified Organisms (GMO) +33 more
doaj +1 more source
, 2019 BACKGROUND/OBJECTIVES: Elongases 2, 4 and 5, encoded by genes ELOVL2, ELOVL4 and ELOVL5, have a key role in the biosynthesis of very long chain polyunsaturated fatty acids (PUFAs).
Deka, R. +8 more
core +1 more source
, 2014 Background The conversions of the n-3 and n-6 fatty acid of plant origin to the C20 and C22 very long chain fatty acids (LCPUFAs) is regulated by several cellular enzymes such as elongases and desaturases.
Høstmark, Arne T +9 more
core +1 more source
Expression of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis genes during zebrafish Danio rerio early embryogenesis [PDF]
, 2009 Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential in important physiological processes, many of which are particularly vital during embryonic development.
Cerdá-Reverter, José Miguel +6 more
core +1 more source
Elongase Reactions as Control Points in Long-Chain Polyunsaturated Fatty Acid Synthesis
PLoS ONE, 2011 Δ6-Desaturase (Fads2) is widely regarded as rate-limiting in the conversion of dietary α-linolenic acid (18:3n-3; ALA) to the long-chain omega-3 polyunsaturated fatty acid docosahexaenoic acid (22:6n-3; DHA). However, increasing dietary ALA or the direct Fads2 product, stearidonic acid (18:4n-3; SDA), increases tissue levels of eicosapentaenoic acid ...
Gregory, M. +4 more
openaire +5 more sources
A single-cell platform for reconstituting and characterizing fatty acid elongase component enzymes
PLOS ONE, 2019 Fatty acids of more than 18-carbons, generally known as very long chain fatty acids (VLCFAs) are essential for eukaryotic cell viability, and uniquely in terrestrial plants they are the precursors of the cuticular lipids that form the organism's outer barrier to the environment.
Alexis A. Campbell +5 more
openaire +5 more sources
DE NOVO FATTY ACID SYNTHESIS BY MICROSOMAL ELONGASES IN TRYPANOSOMES
, 2006 Fatty acids (FAs) up to palmitate (C16) are made de novo by type I synthases in mammals and fungi. Bacteria and plants use type II synthases to make up to stearate (C18).
Lee, SooHee
core
Biosynthesis of Polyunsaturated Fatty Acids in Octopus vulgaris: Molecular Cloning and Functional Characterisation of a Stearoyl-CoA Desaturase and an Elongation of Very Long-Chain Fatty Acid 4 Protein [PDF]
, 2017 Polyunsaturated fatty acids (PUFAs) have been acknowledged as essential nutrients for cephalopods but the specific PUFAs that satisfy the physiological requirements are unknown. To expand our previous investigations on characterisation of desaturases and
Hontoria, Francisco +15 more
core +1 more source
Very long-chain fatty acids accumulate in breast cancer tissue and serum
Cancer Cell InternationalBackground Breast cancer (BC) remains one of the most common cancers with relatively high mortality and is associated with alterations in fatty acid (FA) metabolism.
Alicja Pakiet +10 more
doaj +1 more source