Elongation capacity of polyunsaturated fatty acids in the annelid Platynereis dumerilii
Open BiologyElongation of very long-chain fatty acid (Elovl) proteins plays pivotal functions in the biosynthesis of the physiologically essential long-chain polyunsaturated fatty acids (LC-PUFA).
Marc Ramos-Llorens +6 more
doaj +1 more source
Fatty acid elongase (FAE) systems: An investigation of genetic redundancy
, 2018 Biosynthesis of very long chain fatty acids (VLCFAs) is an integral process for plants, animals & yeast. VLCFAs serve in a variety of biological processes (e.g. protein trafficking, membrane stabilization, precursors for lipid second messengers) and in plants, are components of cuticular waxes, suberin, sphingolipids, phospholipids, seed oils, and GPI ...
openaire +3 more sources
Analyzing the role of lipid elongases in Drosophila development: From barriers to behavior
, 2014 Long chain fatty acids (LCFA) constitute a particular class of lipids whose developmental roles are coming under increasing scrutiny. These LCFAs not only have important cell specific functions but their dysregulation also forms the underlying cause of ...
Gupta, Prachi
core
Functional characterization reveals a diverse array of metazoan fatty acid biosynthesis genes
Molecular Ecology, 2022 J. Boyen +8 more
semanticscholar +1 more source
Fatty acid elongases and desaturases act in concert in modifying the fatty acid acyl chain in respect of length and degree of unsaturation, respectively.
Jacobsson, Anders,, Zadravec, Damir,
core
International Journal of Biological Sciences, 2007 Very long chain fatty acids (VLCFA), either free or as components of glycerolipids and sphingolipids, are present in many organs. Elongation of very long chain fatty acids-4 (ELOVL4) belongs to a family of 6 members of putative fatty acid elongases that ...
Wenmei Li, Roger Sandhoff, Mari Kono, Patricia Zerfas, Vickie Hoffmann, Bryan Char-Hoa Ding, Richard L. Proia, Chu-Xia Deng
doaj
Ecotoxicology and Environmental Safety, 2018 Mariem Fadhlaoui, F. Pierron, P. Couture
semanticscholar +1 more source
Catalytic mechanism of trans-2-enoyl-CoA reductases in the fatty acid elongation cycle and its cooperative action with fatty acid elongases. [PDF]
J Biol ChemKato R, Takenaka Y, Ohno Y, Kihara A.
europepmc +1 more source
Polyunsaturated Fatty Acid Biosynthesis Across Three Trophic Levels in Freshwater Aquaculture: Current Knowledge and Perspectives. [PDF]
Int J Mol SciIvanova E +3 more
europepmc +1 more source
IL-4/IL-13-Driven Dysregulation of Epidermal Lipid Metabolism in Atopic Dermatitis: An Immunometabolic Link Between Type 2 Inflammation and Barrier Dysfunction. [PDF]
CellsAndrzejczak K +5 more
europepmc +1 more source