Transcription factor 19 modulates fatty acid elongation and unfolded protein response to attenuate palmitic acid-induced hepatic dysfunction. [PDF]
Mondal A +5 more
europepmc +1 more source
Engineering Rhodotorula toruloides as a platform organism for de novo synthesis of fatty-acid esters. [PDF]
Wang J +11 more
europepmc +1 more source
A comprehensive discovery platform for ELOVL1 small-molecule inhibitors targeting very long-chain fatty acid synthesis in adrenoleukodystrophy. [PDF]
Holley S +15 more
europepmc +1 more source
Dengue virus is particularly sensitive to interference with long-chain fatty acid elongation and desaturation. [PDF]
Hehner J +7 more
europepmc +1 more source
Breed-specific meat quality and flavor characteristics of Wannan and Chinese Simmental cattle revealed by whole transcriptome and metabolome analysis. [PDF]
Song N +7 more
europepmc +1 more source
A cold manipulation of rainbow trout (Oncorhynchus mykiss) at eyed-stage has few impacts on hepatic lipid metabolism in juveniles. [PDF]
Panserat S +8 more
europepmc +1 more source
Targeted Lipidomics and Transcriptomics Reveal Key Nutrients Regulating Ovarian Development in <i>Coreius guichenoti</i>. [PDF]
Zhu J +7 more
europepmc +1 more source
Fatty Acid Synthesis by Elongases in Trypanosomes [PDF]
All eukaryotic and prokaryotic organisms are thought to synthesize fatty acids using a type I or type II synthase. In addition, eukaryotes extend pre-existing long chain fatty acids using microsomal elongases (ELOs). We have found that Trypanosoma brucei, a eukaryotic human parasite that causes sleeping sickness, uses three elongases instead of type I ...
Kimberly S Paul +2 more
exaly +5 more sources
Cloning and functional characterisation of polyunsaturated fatty acid elongases of marine and freshwater teleost fish [PDF]
Enzymes that lengthen the carbon chain of polyunsaturated fatty acids are key to the biosynthesis of the highly unsaturated fatty acids, arachidonic, eicosapentaenoic and docosahexaenoic acids from linoleic and α-linolenic acids.
Douglas R. Tocher +2 more
exaly +2 more sources

