Results 51 to 60 of about 620,875 (297)

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Demmelmair, Hans, Fidler, N., Koletzko, Berthold, Pohl, A., Sauerwald, T.   +4 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The Effect of Germination and Fermentation on the Physicochemical, Nutritional, and Functional Quality Attributes of Samh Seeds

Foods, 2023
This study investigated the effects of fermentation and germination on the physicochemical, nutritional, functional, and bioactive quality attributes of samh seeds.
Belal M. Mohammed, Isam A. Mohamed Ahmed, Ghedeir M. Alshammari, Akram A. Qasem, Abu ElGasim A. Yagoub, Mohammed Asif Ahmed, Abdullah A. A. Abdo, Mohammed Abdo Yahya   +7 more
doaj   +1 more source

Essential fatty acids (EFA) in haflinger and thoroughbreed mare’s milk [PDF]

, 2002
SUMMARY Mare milk EFA amounts from Thoroughbreed and Haflinger mares from different lactation period in the first 4 months were evaluated. In Thoroughbreed’s milk samples linoleic acid was 22.77% on total fatty acids in colostrum, with a significative ...
Curadi, Maria Claudia, Goracci, Jacopo, Orlandi, Mario   +2 more
core  

How essential are essential fatty acids?

Journal of the American Oil Chemists' Society, 1978
The present article analyzes the symptoms of essential fatty acid deficiency, both in human beings and in animals. The first part of the article describes the interrelationships between linoleic, linolenic and arachidonic acids, and how these acids affect the physiological response in experimental animals.
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Profil Vitamin, Kalsium, Asam Amino Dan Asam Lemak Tepung Jewawut (Setaria Italica L.) Fermentasi [PDF]

, 2017
Foxtail millet (Setaria italica L.) is tropical cereal grains of Poaceae. Foxtail millet starch content is quite high, so it has the potential to be used as food raw material; This study has been conducted by making foxtail millet flour fermented with ...
Soeka, Y. S. (Yati), Sulistiani, S. (Sulistiani)   +1 more
core  

Commercial Applications of Microalgae [PDF]

, 2006
The first use of microalgae by humans dates back 2000 years to the Chinese, who used Nostoc to survive during famine. However, microalgal biotechnology only really began to develop in the middle of the last century.
Duran, Elie, Isambert, Arsène, Joannis-Cassan, Claire, Spolaore, Pauline   +3 more
core   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
core   +2 more sources