Results 101 to 110 of about 94,621 (264)

Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

Molecular Metabolism
Objective: Exposure of adipocytes to ‘cool’ temperatures often found in the periphery of the body induces expression of Stearoyl-CoA Desaturase-1 (Scd1), an enzyme that converts saturated fatty acids to monounsaturated fatty acids. The goal of this study
Hiroyuki Mori, Sydney K. Peterson, Rachel C. Simmermon, Katherine A. Overmyer, Akira Nishii, Emma Paulsson, Ziru Li, Annie Jen, Romina M. Uranga, Jessica N. Maung, Warren T. Yacawych, Kenneth T. Lewis, Rebecca L. Schill, Taryn Hetrick, Ryo Seino, Ken Inoki, Joshua J. Coon, Ormond A. MacDougald   +17 more
doaj   +1 more source

Associations of Adiposity With Gut Microbiota Composition Among Adults—Results From a Federated Analysis of Individual Participant Data From Eight European Observational Studies

Obesity Reviews, EarlyView.
ABSTRACT Gut microbiota may contribute to the adiposity‐associated disease risk, but human studies reported inconsistent associations of adiposity with gut microbiota composition. We examined associations of body mass index (BMI) with alpha diversity and relative microbial abundance at the phylum and genus taxonomic levels (based on 16S rRNA amplicon ...
Carolina Schwedhelm, Mariona Pinart, Sofia K. Forslund‐Startceva, Kolade Oluwagbemigun, Andreas Dötsch, Kristina Schlicht, Florian Schwarz, Sofia M. Siampani, Demetris Avraam, Maria De Angelis, Jildau Bouwman, Patrizia Brigidi, Giovanna Caderni, Francesco Maria Calabrese, Rafael R. C. Cuadrat, Carlotta De Filippo, Francesca De Filippis, Danilo Ercolini, Marco Fabbrini, Matthias Laudes, Ute Nöthlings, Serdar Özsezen, Itai Sharon, Matthias B. Schulze, Silvia Turroni, Francesco Vitali, Tobias Pischon, Katharina Nimptsch   +27 more
wiley   +1 more source

SBP‐Box Transcription Factor JcSPL9 Regulates Both Seed Yield and Oil Content in the Biofuel Plant Jatropha curcas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Jatropha curcas is a promising feedstock for biodiesel and bio‐jet fuels production; however, its seed yield is constrained by limited inflorescences. SPL9 is a member of the SBP‐box gene family that promotes the juvenile‐to‐adult phase transition.
Mingyong Tang, Xue Bai, Yaoping Xia, Ping Huang, Zeng‐Fu Xu   +4 more
wiley   +1 more source

Portable Photobioreactor‐Based Stock Culture of Skeletonema costatum for Sustainable Live Feed Production in Shrimp Hatcheries of Bangladesh

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
This study develops a portable photobioreactor in which Skeletonema costatum growth is optimized using Box‐Behnken design. The physico‐chemical parameters, such as temperature, salinity and pH are standardized to maximize culture duration and biomass production. The optimized biomass exhibits high protein content and essential fatty acids, particularly
Zahidul Islam, Turabur Rahman, Shafiqur Rahman, Anuradha Bhadra   +3 more
wiley   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Milk Fatty Acid Dynamics in Cows Grazing Standard and Multispecies Pastures Under Two Management Systems

New Zealand Journal of Agricultural Research, Volume 69, Issue 2, April 2026.
This study evaluated the influence of three pasture‐management systems on milk fatty acid (FA) profiles in New Zealand dairy cows: standard–contemporary (STD–CON), diverse–contemporary (DIV–CON), and diverse–regenerative (DIV–REG). The STD–CON pastures consisted of ryegrass–clover, whereas diverse pastures included up to 16 species of grasses, legumes,
Yaliska Moreno‐González, Nicolas López‐Villalobos, Daniel Donaghy, Ignacio F. López, Benjamin Carter, Fernando J. Roca Fraga, J. Eruera Tait‐Jamieson, Stephen E. Holroyd, Alastair MacGibbon   +8 more
wiley   +1 more source

Effects of Phenolic‐Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP‐Sarc Project

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic‐rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB) (fructooligosaccharides and inulin), to improve skeletal muscle mass and function in home‐dwelling older adults (60–80 ...
Maria Besora‐Moreno, Claudia Jiménez‐ten Hoevel, Judit Queral, Glòria Bernal, Laura Pérez‐Merino, José Puzo, Laura Conangla‐Ferrin, Leann Constance Sleebos, Wout van Helden, Elisabet Llauradó, Rosa M. Valls, Rosa Solà, Anna Pedret   +12 more
wiley   +1 more source

Dietary essential oils modulate post‐mortem oxidative damage in trout fillets exposed to slaughter stress during frozen storage

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3686-3695, April 2026.
Abstract BACKGROUND Slaughter is a critical phase in aquaculture that can severely compromise both animal welfare and product quality. Stress responses triggered during this stage may accelerate post‐mortem biochemical degradation and promote oxidative damage in fish fillets. Essential oils, known for their antioxidant and anti‐inflammatory properties,
Lucía Méndez, Giulia Secci, Lorena Barros, Gabriel Dasilva, Giuliana Parisi, Isabel Medina   +5 more
wiley   +1 more source

Effects of feeding almond hulls to light lambs on carcass characteristics and meat quality

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3876-3884, April 2026.
Abstract BACKGROUND Almond hulls (AH) are the main by‐product of almond processing for human consumption and contain bioactive compounds that can improve meat quality. Although AH are used as feed for dairy cows in some countries, information on their potential effects on meat quality is limited.
Adriana Recalde, Trinidad de Evan, Almudena Cabezas, María Teresa Díaz‐Chirón, Javier Mateo, Rafael A. Roldán, Silvia López‐Feria, María Dolores Carro   +7 more
wiley   +1 more source