Results 271 to 280 of about 304,657 (328)

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

Aging Cell, EarlyView.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel, J. Candia, C. Ubaida‐Mohien, T. Tanaka, A. Z. Moore, M. Zhu, G. Fantoni, S. Church, J. D'Agostino, J. Fan, N. Shehadeh, S. De, E. Lehrmann, M. Kaileh, E. Simonsick, R. Sen, J. M. Egan, L. Ferrucci   +17 more
wiley   +1 more source

Association between the dietary omega-6 to omega-3 fatty acid ratio and age-related macular degeneration in Korean adults. [PDF]

Nutr J
Jang W, Kim Y, Kim H.
europepmc   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

Omega-3 Fatty Acids for the Treatment of Bipolar Disorder Symptoms: A Narrative Review of the Current Clinical Evidence. [PDF]

Mar Drugs
Psara E, Papadopoulou SK, Mentzelou M, Voulgaridou G, Vorvolakos T, Apostolou T, Giaginis C.   +6 more
europepmc   +1 more source

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

Aging Cell, EarlyView.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan, Hongxia Cai, Fang Ye, Wentao Xu, Zhihang Huang, Jingyuan Zhu, Yiwen Gong, Yutong Li, Anastasia Ngozi Ezemaduka, Shan Gao, Shunqi Liu, Guojun Li, Hao Li, Jing Yang, Junyu Ning, Bo Xian   +15 more
wiley   +1 more source

Nutritional Value and Health Implications of Meat from Monogastric Animals Exposed to Heat Stress. [PDF]

Nutrients
Prates JAM.
europepmc   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos, Martin H. Teicher, Robert M. Post   +2 more
wiley   +1 more source

Effects of Perilla Seed Oil on Blood Lipids, Oxidative Stress, and Inflammation in Hyperlipidemic Rats. [PDF]

Foods
Pothinam S, Putpim C, Siriwoharn T, Jirarattanarangsri W.   +3 more
europepmc   +1 more source

Feather forensics: tracing the origins of parrots in wildlife trade with stable isotopes and citizen science

Animal Conservation, EarlyView.
To supply high demand for exotic pets, animals are harvested illegally from the wild and laundered as captive bred. However, there are currently limited methods to identify captive or wild origins of wildlife. We assessed the accuracy of stable isotope analysis of feathers to identify differences in diets, and therefore captive and wild origins, of ...
K. G. W. Hill, S. Delean, T. Hall, J. J. Tyler, O. C. Stringham, P. Cassey   +5 more
wiley   +1 more source

Metabolic dysfunction-associated steatotic liver disease and omega-6 polyunsaturated fatty acids: Friends or foes. [PDF]

World J Hepatol
Hegazy MA, Ahmed SM, Sultan SM, Afifi OF, Mohamed MA, Azab AE, Hassanen MA, Zaben RK.   +7 more
europepmc   +1 more source