Results 61 to 70 of about 85,629 (256)

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Omega-3 Polyunsaturated Fatty Acids in Depression

International Journal of Molecular Sciences
Omega-3 polyunsaturated fatty acids have received considerable attention in the field of mental health, in particular regarding the treatment of depression. This review presents an overview of current research on the role of omega-3 fatty acids in the prevention and treatment of depressive disorders.
Anna Serefko, Monika Elżbieta Jach, Marlena Pietraszuk, Małgorzata Świąder, Katarzyna Świąder, Aleksandra Szopa   +5 more
openaire   +3 more sources

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Influence of omega-3 fatty acids on post-traumatic stress disorder: prospective cohort study and Mendelian randomisation findings

European Journal of Psychotraumatology
Background and Objectives: Omega-3 fatty acids have positive effects on mental health. This study aimed to explore the association between plasma omega-3 fatty acid levels and the risk of post-traumatic stress disorder (PTSD).Methods: This study explored
Ming Chen, Haozhang Huang, Yong Liu, Cailan Hou, Shiqun Chen   +4 more
doaj   +1 more source

Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios

Nutrition Journal, 2009
Background This research was conducted to explore the relationships between the levels of omega-3 fatty acids in serum phospholipid and key fatty acid ratios including potential cut-offs for risk factor assessment with respect to coronary heart disease ...
Rowe William, Wlodek Mike, Holub Bruce J, Piekarski Jerry   +3 more
doaj   +1 more source

Omega-3 fatty acids for intermittent claudication

Cochrane Database of Systematic Reviews
Peripheral artery disease (PAD) is a progressive disorder characterised by stenosis or occlusion of arteries, or both, due to arteriosclerosis. Intermittent claudication (IC) and diminished walking ability are often present as the main symptoms of PAD.
Mohammady, Mina, Brown, Tamara, Radmehr, Maryam, Shamsoddin, Erfan, Janani, Leila   +4 more
openaire   +2 more sources

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

Enhancing brain health through omega fatty acids: Ahiflower oil and oleic acid as novel plant-based nootropic ingredients targeting the microbiome–Gut–Brain Axis

Future Foods
Neurodegenerative disorders are a growing global health concern, prompting interest in dietary factors that may influence the development and progression of conditions such as Alzheimer’s disease, Parkinson’s disease, and other age-related cognitive ...
Anita Fuambi, Robert Cumming, Ramak Esfandi, Raymond H. Thomas   +3 more
doaj   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Effect of dietary selenium and omega-3 fatty acids on muscle composition and quality in broilers

Lipids in Health and Disease, 2007
Background Human health may be improved if dietary intakes of selenium and omega-3 fatty acids are increased. Consumption of broiler meat is increasing, and the meat content of selenium and omega-3 fatty acids are affected by the composition of broiler ...
Hetland Harald, Wold Jens P, Bernhoft Aksel, Eich-Greatorex Susanne, Haug Anna, Christophersen Olav A, Sogn Trine   +6 more
doaj   +1 more source