Results 61 to 70 of about 183,416 (257)
Advanced Science, EarlyView.Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li +12 more
wiley +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
The omega-6/omega-3 fatty acid ratio: health implications
Oléagineux, Corps gras, Lipides, 2010 Today, Western diets are characterized by a higher omega-6 and a lower omega-3 fatty acid intake, whereas during the Paleolithic period when human’s genetic profile was established, there was a balance between omega-6 and omega-3 fatty acids.
Simopoulos Artemis P.
doaj +1 more source
Nutrition Considerations in Aquaculture: The Importance of Omega-3 Fatty Acids in Fish Development and Human Health [PDF]
, 2012 This report examines the importance of Omega-3 fatty acids to both human health and fish development. The study considers nutritional requirements for different species of fish and different stages of development, as well as methods to increase the ...
Ako, Harry +3 more
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Comparison of fatty acid profile in lamb meat and baby food based on lamb meat [PDF]
, 2009 The aim of this study was to compare the fatty acid (FA) profile of fresh lamb meat with those of baby foods based on lamb meat. For this purpose, samples of commercial homogenized (HO) and lyophilized (LIO) baby food based on lamb meat and fresh lamb ...
Andrea Serra +6 more
core +2 more sources
A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
Advanced Science, EarlyView.An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source
Comparison of protein, total fat, and omega-3 fatty acids content in yellowtail catfish (Pangasius pangasius) and long tail shad (Hilsa (clupea) macrura) in raw and pressurized fish [PDF]
, 2014 Omega-3 fatty acids have been shown to reduce the risk of chronic diseases like cardiovascular disease and cancer as well as promote brain development among infants and children.
Rahmat, Asmah +2 more
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Advanced Science, EarlyView.TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic health
California Agriculture, 2011 This article focuses on the role of omega-3 fatty acids as precursors for lipid signaling molecules known as oxylipins. Although omega-3 fatty acids are beneficial in autoimmune disorders, inflammatory diseases and heart disease, they are generally ...
A Zivkovic, N Telis, J German, B Hammock
doaj +2 more sources
Fatty acids in fish and beef and their nutritional values: a review. [PDF]
, 2009 This review aims to summarize the latest developments and recent knowledge regarding the fatty acids in fish and beef, their profiles and nutritional values.
A., Mohamed +2 more
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