Results 81 to 90 of about 19,128,233 (302)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Biobehavioural and cerebral hemodynamic effects of omega-3 polyunsaturated fatty acids in healthy individuals [PDF]

The omega-3 polyunsaturated fatty acids (n-3 PUFAs) are a unique class of fatty acids that cannot be manufactured by the body, and must be acquired via dietary sources.
Jackson, Philippa
core  

Maternal intake of fatty acids during pregnancy and allergies in the offspring [PDF]

, 2011
Fatty acids (FA) are known to have a number of immunological effects and, accordingly, may play a role in the development of allergic diseases. We investigated the effect of maternal intake of FA during pregnancy on the risk of allergic rhinitis, wheeze ...
Veijola, Riitta, Maijaliisa Erkkola, Jorma Ilonen, Suvi Ahonen, Erkkola, Maijaliisa, Riitta Veijola, Suvi M. Virtanen, Mikael Knip, Knip, Mikael, Virtanen, Suvi M., Kronberg-Kippila, Carina, Simell, Olli, Mirka Lumia, Minna Kaila, Nwaru, Bright I., Kaila, Minna, Nwaru, Bright I, Olli Simell, Bright I. Nwaru, Lumia, Mirka, Virtanen, Suvi M, Ilonen, Jorma, Carina Kronberg-Kippilä, Ahonen, Suvi   +23 more
core   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic health

California Agriculture, 2011
This article focuses on the role of omega-3 fatty acids as precursors for lipid signaling molecules known as oxylipins. Although omega-3 fatty acids are beneficial in autoimmune disorders, inflammatory diseases and heart disease, they are generally ...
A Zivkovic, N Telis, J German, B Hammock
doaj   +2 more sources

How Do Omega-3 and Omega-6 Fatty Acids Influence the Development of Common Acne?

Journal of Education, Health and Sport
Introduction: Acne is one of the most common skin problems affecting people worldwide, especially young individuals. Despite many years of research into the etiology of acne, its exact causes remain a subject of debate.
Paweł Rogalski, Malwina Pomianek, Katarzyna Makara, Victor Celarek, Karolina Makara   +4 more
doaj   +1 more source

ROLE OF OMEGA-3 FATTY ACIDS ON POSTPARTUM DEPRESSION [PDF]

Introduction: Women in child-bearing age are at risk of postpartum depression. Several drugs have been introduced for treatment, but because of their side effects and also breast feeding women's desire for dietary complements rather than chemical drugs ...
قوجازاده, مرتضی, نوروزی پناهی, لیلا, رنجبر کوچکسرایی, فاطمه, ایوان بقاء, ریحانه   +3 more
core   +1 more source

Consumption of a high n-3 polyunsaturated fatty acid diet during gradual mild physiological stress in rats. [PDF]

, 2015
n-3 Polyunsaturated fatty acids (n-3PUFAs) may be beneficial for anxiety and depression under stressful conditions. Studies however, typically utilise physical or sudden physiological stress, while gradual physiological stress is also relevant to human ...
Johnson, A.K., Beltz, T.G., Appleton, Katherine, Grippo, A.J., Appleton, K.M., Johnson, A.K   +5 more
core   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source