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Endoplasmic reticulum stress enhances unsaturated fatty acid-induced hepatocyte injury in human pluripotent stem cell-derived hepatic culture [PDF]
BMC GastroenterologyBackground The liver is a central organ involved in lipid metabolism. Hepatocytes synthesize fatty acids and triglycerides under conditions of excess energy while decomposing fats by β-oxidation under conditions of energy deficiency.
Takuma Araki +4 more
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Unsaturated fatty acids induce non‐canonical autophagy [PDF]
The EMBO Journal, 2015 To obtain mechanistic insights into the cross talk between lipolysis and autophagy, two key metabolic responses to starvation, we screened the autophagy-inducing potential of a panel of fatty acids in human cancer cells. Both saturated and unsaturated fatty acids such as palmitate and oleate, respectively, triggered autophagy, but the underlying ...
Niso Santano, Mireia +26 more
openaire +6 more sources
Unsaturated Fatty Acids and Pain
Biological and Pharmaceutical Bulletin, 2011 Fatty acids, which are the essential nutrients for humans, are an important source of energy and an essential component of cell membranes. They also function as signal transduction molecules in a range of biological phenomena. Recently, an increasing number of physiologic and pharmacologic reports on fatty acids have improved our understanding of the ...
Shogo, Tokuyama, Kazuo, Nakamoto
openaire +4 more sources
Unsaturated Fatty Acids and Their Immunomodulatory Properties
Biology, 2023 Simple Summary Diet can influence human health in both positive and negative ways. Ω-3 polyunsaturated fatty acids have an overall positive effect on humans. The sources of these fatty acids are primarily plant seeds and fish.
Salvatore J Coniglio +2 more
semanticscholar +1 more source
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2022 This review highlights the key role of fatty acid desaturases in the synthesis of naturally occurring, more common and not unsaturated fatty acids. The three major classes of fatty acid desaturases, such as acyl‐lipid, acyl‐acyl carrier protein and acyl ...
Michela Cerone, T. K. Smith
semanticscholar +1 more source
JFMR-Journal of Fisheries and Marine Research, 2021 The microalgae Spirulina sp. is a potential biological resource. Utilization of Spirulina sp. very broad in various industrial fields such as nutraceutical, food, cosmetic and pharmaceutical.
Heder Djamaludin, Anies Chamidah
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The Potential of Fatty Acids and Their Derivatives as Antifungal Agents: A Review
Toxins, 2022 Fungal contamination presents several problems: in humans, health issues arise from infections with opportunistic filamentous fungi and yeast, while in food, fungi cause spoilage and, in particular, in the case of mycotoxigenic fungi, can cause serious ...
Ana Guimarães, A. Venâncio
semanticscholar +1 more source
Proximate composition and fatty acids profiling of Seahorse originated from Simeulue, Aceh-Indonesia [PDF]
E3S Web of Conferences, 2022 The aim of this study was to determine the proximate composition, quantitative of fatty acids analysis as well as the content in the seahorse sample, Hippocampus sp which originated from Sibigo waters, Simeulue, Aceh, Indonesia.
Abdullah Abbas Muhammadar +4 more
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Plant Unsaturated Fatty Acids: Multiple Roles in Stress Response
Frontiers in Plant Science, 2020 Land plants are exposed to not only biotic stresses such as pathogen infection and herbivore wounding, but abiotic stresses such as cold, heat, drought, and salt.
Mei He, N. Ding
semanticscholar +1 more source
Plant Unsaturated Fatty Acids: Biosynthesis and Regulation
Frontiers in Plant Science, 2020 In most plants, major unsaturated fatty acids (UFAs) are three C18 species, namely, oleic (18:1), linoleic (18:2), and α-linolenic (18:3) acids. These simple compounds play multiple crucial roles in planta and are also important economic traits of oil ...
Mei He, Chun-Xue Qin, Xu Wang, N. Ding
semanticscholar +1 more source