Results 81 to 90 of about 630,244 (294)

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

open access: yesAdvanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu   +15 more
wiley   +1 more source

Investigating the Profile of Saturated and Unsaturated Fatty Acids of Camelina Oil in Response to Salinity Stress and Polyamines [PDF]

open access: yesTulīd va Farāvarī-i Maḥṣūlāt-i Zirā̒ī va Bāghī
In order to investigate the profile of saturated and unsaturated fatty acids of camellia oil in response to salinity stress and polyamines, an experiment was conducted in March 2022 in a factorial layout based on a completely randomized design as pot ...
E. Gholinezhad, Sh. Kazemi, B. Lalehgani
doaj  

Determination of Fatty Acid in Asparagus by Gas Chromatography

open access: yesİstanbul Üniversitesi Veteriner Fakültesi Dergisi, 2016
Asparagus contain a lot of macronutrients and micronutrients including folate, dietary fibre (soluble and insoluble) and phenolic compounds. Also asparagus is a good source of unsaturated linoleic and linolenic fatty acids which are precursors for ...
Zehra HAJRULAI-MUSLIU   +5 more
doaj   +1 more source

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

open access: yesAdvanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing   +4 more
wiley   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo   +9 more
wiley   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

open access: yesAggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail   +5 more
wiley   +1 more source

In vitro esterification of cholesterol by pancreatic juice and by acetone powder extracts of small intestine: the effect of unsaturated fatty acids upon esterification with saturated fatty acids

open access: yesJournal of Lipid Research, 1965
The esterification of cholesterol by rat pancreatic juice and by extracts of acetone powders of rat small intestine was studied with palmitic, stearic, oleic, linoleic, and linolenic acids.
S.N. Shah, W.J. Lossow, I.L. Chaikoff
doaj  

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou   +3 more
wiley   +1 more source

Analysis of fatty acid methyl esters by a gas—liquid chromatography—chemical ionization mass spectrometry computer system1

open access: yesJournal of Lipid Research, 1978
The technique of gas-liquid chromatography-chemical ionization mass spectrometry can easily identify trace peaks and unresolved peaks on gas–liquid chromatography, utilizing MH+ ions of chemical ionization mass spectra.
T Murata
doaj  

Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A

open access: yesAngewandte Chemie International Edition, EarlyView.
A biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme.
Andrea Nigl   +11 more
wiley   +1 more source

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