Results 221 to 230 of about 123,118 (306)

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

From plant to fabric: Environmental opportunities associated with annatto dye for sustainable development in the textile industry

open access: yesColoration Technology, EarlyView.
Abstract Natural dyes are compounds that occur naturally in several organisms and are classified based on chemical structure and application method. The literature cites several natural dyes used in industrial transformation processes. Annatto dye is used in the food industry, and its biological pigment is extracted from the annatto seed. However, this
Marcel Jefferson Gonçalves   +5 more
wiley   +1 more source

Delipidisation of wool fibres and the subsequent beneficial properties of delipidised wool fibres

open access: yesColoration Technology, EarlyView.
Abstract Wool fibres are complex matrices of proteins and fatty acids/lipids found both internally and externally. 18‐methyleicosanoic acid (18‐MEA) is covalently bound to the surface of the fibre via a thio‐ester link, and is considered one of the most important lipids as it is responsible for the hydrophobic properties of wool fibres.
Jamie A. Hawkes, David M. Lewis
wiley   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

open access: yesCell Proliferation, EarlyView.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang   +4 more
wiley   +1 more source

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