Results 91 to 100 of about 4,584 (262)

Integrated lipidomics and transcriptomics to elucidate heterogeneity between intramuscular and abdominal fat and identify serum and liver markers for their differential deposition in chickens

Poultry Science
During broiler production, moderate intramuscular fat (IMF) deposition improves meat quality, whereas excessive abdominal fat (AF) increases production cost.
Zhongzhen Lin, Xiaoyan Song, Jialei Chen, Jie Qu, Chaowu Yang, Lingqian Yin, Donghao Zhang, Yuan Tang, Chunlin Yu, Yiping Liu   +9 more
doaj   +1 more source

Semi-selective fatty acyl reductases from four heliothine moths influence the specific pheromone composition.

PLoS ONE, 2012
BackgroundSex pheromones are essential in moth mate communication. Information on pheromone biosynthetic genes and enzymes is needed to comprehend the mechanisms that contribute to specificity of pheromone signals.
Asa K Hagström, Marjorie A Liénard, Astrid T Groot, Erik Hedenström, Christer Löfstedt   +4 more
doaj   +1 more source

A Single‐Capillary Open Microfluidic Probe for Robust and Versatile Spatial Multi‐Omics Using Ambient Mass Spectrometry Imaging

Advanced Science, EarlyView.
This study reports a knot‐shaped single‐capillary open microfluidic probe (Knot‐probe) for robust and versatile spatial omics, enabling ambient mass spectrometry imaging with high spatial resolution, throughput, and structure‐resolved capability. Knot‐probe mitigates the trade‐off between analytical performance and operational robustness, providing an ...
Xiangyu Zhu, Yunkai Li, Jianing Wang, Chengyi Xie, Lei Guo, Yanyan Chen, Thomas Ka‐Yam Lam, Shao‐Wen Shi, Kun Wang, Baoliang Chen, Zongwei Cai   +10 more
wiley   +1 more source

Lipidomics and Transcriptomics Analyses Reveal Dietary Complex Plant Extracts Improve Lipid Composition of Back Fat in Sheep

Animals
Fatty acid contributes notably to meat nutrition value. A previous study investigated how complex plant extracts (CPE) can improve the fatty acid composition of ruminants, but the molecular mechanism remains unknown.
Hui Guo, Ruixue Nie, Tao Guo, Chang Gao, Jinju Mao, Yuchao Hu, Wenwen Wang, Na Liu, Xiaoping An, Jingwei Qi, Yuan Wang   +10 more
doaj   +1 more source

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez, Karoline Lantzsch, Romain Topalian, Nadine Gunder, Philipp Hubel, Katharina Schindowski, Jens Pfannstiel, Thomas Hummel   +7 more
wiley   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Alterations Of Glycerophospholipid And Fatty Acyl Metabolism In Multiple Brain Regions Of Schizophrenia Microbiota Recipient Mice

Neuropsychiatric Disease and Treatment, 2019
Weiwei Liang,1–3,* Yu Huang,1,3,* Xunmin Tan,1,3,* Jing Wu,3,4 Jiajia Duan,3,4 Hanping Zhang,1,3 Bangmin Yin,1,3 Yifan Li,1,3 Peng Zheng,1,3 Hong Wei,5 Peng Xie1,3 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical ...
Liang W, Huang Y, Tan X, Wu J, Duan J, Zhang H, Yin B, Li Y, Zheng P, Wei H, Xie P   +10 more
doaj  

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

Angewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari, Leon F. Schwarz, Luca Schlautmann, Kai Schließmann, Christopher Slotman, Nina von Felten, Claus‐Michael Lehr, Rolf Müller, Alexander F. Kiefer, Jörn Piel, Florian Hubrich   +10 more
wiley   +1 more source

Targeted lipidomics meets transcriptomics: how cinobufagin rewires fatty acid, sphingolipid, and glycerophospholipid metabolism to combat hepatoma cell growth

Frontiers in Pharmacology
IntroductionHepatocellular carcinoma (HCC) is a common malignant tumor, is characterized by an early stage that is not easy to diagnose and a high mortality rate in the late stage, which is a serious threat to patients' lives.
Wanjun Shao, Congying Yu, Rufei Xu, Xiaoqian Rong, Ailin Yang   +4 more
doaj   +1 more source

Alkali‐Catalyzed Synthesis of Acylglycerol Estolides Exclusively from Castor Oil

Journal of the American Oil Chemists' Society, EarlyView.
This work advances sustainable chemistry by converting renewable castor oil into high‐performance estolides via solvent‐free, low‐energy catalysis. ABSTRACT Estolides are oligomers composed of fatty acid (FA) monomers linked through secondary ester bonds located along the mid‐chain region.
Lucas Natã de Melo, Simoni Margareti Plentz Meneghetti, Mario Roberto Meneghetti, Janaína Heberle Bortoluzzi   +3 more
wiley   +1 more source