Results 31 to 40 of about 779,655 (355)

Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases

Frontiers in Pharmacology, 2022
Thyroid hormone/thyroid hormone receptor (TH/TR) axis is characterized by TH with the assistance of plasma membrane transporters to combine with TR and mediate biological activities.
Qianyu Tang, Min Zeng, Linxi Chen, Nian Fu, Nian Fu   +4 more
doaj   +1 more source

"Efficacy of SGLT2 inhibitors in non-diabetic non-alcoholic fatty liver disease: a systematic review and meta-analysis". [PDF]

J Diabetes Metab Disord
Abbas MS, Dandamudi M, Rehman T, Faizan MA, Zahra I, Mojica JC, Ahmed MR, Bai K, Shakeel I, Shahzad Z, Giorgi J.   +10 more
europepmc   +3 more sources

Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced GeneSummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Background and Aims: Butyric acid is an intestinal microbiota-produced short-chain fatty acid, which exerts salutary effects on alleviating nonalcoholic fatty liver disease (NAFLD).
Ze-Hua Zhao, Zi-Xuan Wang, Da Zhou, Yamei Han, Fengguang Ma, Zhimin Hu, Feng-Zhi Xin, Xiao-Lin Liu, Tian-Yi Ren, Feifei Zhang, Yaqian Xue, Aoyuan Cui, Zhengshuai Liu, Jinyun Bai, Yuxiao Liu, Genxiang Cai, Weitong Su, Xiaozhen Dai, Feng Shen, Qin Pan, Yu Li, Jian-Gao Fan   +21 more
doaj   +1 more source

Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]

, 2018
The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo, Bellanti, Francesco, Blonda, Maria, di Bello, Giorgia, Facciorusso, Antonio, Iannelli, Giuseppina, Iuliano, Luigi, Poli, Giuseppe, Serviddio, Gaetano, Tamborra, Rosanna, Vendemiale, Gianluigi, Villani, Rosanna   +11 more
core   +2 more sources

Pathomechanism of Insulin Resistance in Men with Central Obesity: Correlation of GGT, GPx, Hs-CRP and Plasma Total Cysteine [PDF]

, 2013
BACKGROUND: Gamma glutamyltransferase (GGT) was reported recently to be associated with inflammation, oxidative stress and increased amino acid. However, role of GGT in insulin resistance pathomechanism is not exactly known.
Patellongi, I. (Ilhamjaya), Ritawaty, R. (Ritawaty), Sandra, F. (Ferry), Sukmawati, I. R. (Indriyanti)   +3 more
core   +4 more sources

Gut metabolomics and 16S rRNA sequencing analysis of the effects of arecoline on non-alcoholic fatty liver disease in rats

Frontiers in Pharmacology, 2023
Introduction: Non-alcoholic fatty liver disease (NAFLD) has gradually become the primary cause of fatty liver disease. Betel nuts have been used to treat gastrointestinal diseases.Methods: In the present study, we analyzed the pathology, serology, gut ...
Lingping Zhu, Lingping Zhu, Duo Li, Xuefeng Yang, Xuefeng Yang   +4 more
doaj   +1 more source

A Novel Prescription Digital Therapeutic Option for the Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease

Gastro Hep Advances
Background and Aims: Metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis are pressing public health problems occurring alongside the rising prevalence of obesity and diabetes.
Naim Alkhouri, Katherine Edwards, Mark Berman, Heather Finn, Rafael Escandon, Paul Lupinacci, Nicole Guthrie, Angie Coste, Jesus Topete, Mazen Noureddin   +9 more
doaj   +1 more source

Nonalcoholic Fatty Liver Disease [PDF]

, 2020
AbstractNonalcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of the metabolic syndrome (MetS) and comprises one of the largest health threats of the twenty-first century. In this chapter, we review the current state of knowledge of NAFLD and underline the striking similarities with atherosclerosis.
Ding, Lingling, Oligschlaeger, Yvonne, Shiri-Sverdlov, Ronit, Houben, Tom   +3 more
openaire   +3 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Feasibility study and reference values of FibroScan 502 with M probe in healthy preschool children aged 5 years

BMC Pediatrics, 2019
Background Transient elastography (TE) using FibroScan with M probe has been widely used in adults for controlled attenuation parameter (CAP) and liver stiffness measurement (LSM).
Jing Zeng, Xi Zhang, Chao Sun, Qin Pan, Wen-Yi Lu, Qian Chen, Li-Su Huang, Jian-Gao Fan   +7 more
doaj   +1 more source