Results 31 to 40 of about 2,963,117 (406)

Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association.

Arteriosclerosis, Thrombosis and Vascular Biology, 2022
Nonalcoholic fatty liver disease (NAFLD) is an increasingly common condition that is believed to affect >25% of adults worldwide. Unless specific testing is done to identify NAFLD, the condition is typically silent until advanced and potentially ...
P. B. Duell, F. Welty, M. Miller, A. Chait, Gmerice Hammond, Z. Ahmad, D. Cohen, J. Horton, G. Pressman, P. Toth   +9 more
semanticscholar   +1 more source

Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis

Lipids in Health and Disease, 2019
Background Ceramide plays pathogenic roles in nonalcoholic fatty liver disease (NAFLD) via multiple mechanisms, and as such inhibition of ceramide de novo synthesis in the liver may be of therapeutically beneficial in patients with NAFLD.
Rui-Xu Yang, Qin Pan, Xiao-Lin Liu, Da Zhou, Feng-Zhi Xin, Ze-Hua Zhao, Rui-Nan Zhang, Jing Zeng, Liang Qiao, Chun-Xiu Hu, Guo-Wang Xu, Jian-Gao Fan   +11 more
doaj   +1 more source

In-depth analysis of de novo lipogenesis in non-alcoholic fatty liver disease: Mechanism and pharmacological interventions

Liver Research, 2023
Non-alcoholic fatty liver disease (NAFLD) is characterized by the abnormal buildup of lipids in the liver tissue. Non-alcoholic fatty liver (NAFL) may progress to non-alcoholic steatohepatitis.
Zhixian Zhu, Xiaoxun Zhang, Qiong Pan, Liangjun Zhang, Jin Chai   +4 more
doaj   +1 more source

Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease [PDF]

, 2019
Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For
Aguirre López, Leixuri, De Luis Román, Daniel Antonio, Lasa Elguezua, Arrate, Martín Diana, Ana Belén, Milton Laskibar, Iñaki, Miranda Gómez, Jonatan, Rico Bargues, Daniel   +6 more
core   +2 more sources

The AMPK pathway in fatty liver disease

Frontiers in Physiology, 2022
Lipid metabolism disorders are the primary causes for the occurrence and progression of various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease (AFLD) caused by a high-fat diet and ethanol.
Chunqiu Fang, Jianheng Pan, Ning Qu, Yuting Lei, Jiajun Han, Jingzhou Zhang, D. Han   +6 more
semanticscholar   +1 more source

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice [PDF]

, 2017
© 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake.
Asai, Baldock, Bieghs, Bora, Cani, Chan, Chawla, Del Ben, DeLuca, Dongiovanni, Drewnowski, George, Giugliano, Glaros, Hummasti, Iwaki, Jorde, Jump, Kalra, Karbowska, Kennedy, Kheder, Kitson, Kleiner, Kraakman, Lira, Livak, Lytle, Machado, Madar, Marcotorchino, Merat, Minto, Oh, Okamoto, Parekh, Pham, Roth, Saraswathi, Schwen, Sergeev, Shu, Subramanian, Teramoto, Tintut, Vanlint, Wortsman, Wouters, Yin, Zhang, Zhang   +50 more
core   +1 more source

Association Between Monocyte to High-Density Lipoprotein Cholesterol Ratio and Risk of Non-alcoholic Fatty Liver Disease: A Cross-Sectional Study

Frontiers in Medicine, 2022
Background:Non-alcoholic fatty liver disease (NAFLD) is a global health problem affecting more than a quarter of the entire adult population. Both monocytes and high-density lipoprotein cholesterol (HDL-C) were found to participate in the progression of ...
Liping Wang, Liping Wang, Jinzhong Dong, Miao Xu, Li Li, Naibin Yang, Naibin Yang, Guoqing Qian, Guoqing Qian   +8 more
doaj   +1 more source

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

Scientific Reports, 2017
Non-alcoholic steatohepatitis (NASH) is an epidemic metabolic disease with limited therapeutic strategies. Cumulative data support the pivotal role of gut microbiota in NASH.
Da Zhou, Qin Pan, Feng Shen, Hai-xia Cao, Wen-jin Ding, Yuan-wen Chen, Jian-gao Fan   +6 more
doaj   +1 more source

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana, Angelico, Francesco, Baratta, Francesco, DEL BEN, Maria, Pastori, Daniele, Perri, Ludovica, Polimeni, Licia, Violi, Francesco   +7 more
core   +1 more source

Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma

Nature Communications, 2021
The gut microbiota is reported to modulate the immune response in hepatocellular carcinoma (HCC). Here, we employ metagenomic and metabolomic studies to characterise gut microbiota in patients with non-alcoholic fatty liver disease (NAFLD) related ...
J. Behary, N. Amorim, Xiao-Tao Jiang, A. Raposo, L. Gong, E. McGovern, Ragy Ibrahim, F. Chu, C. Stephens, H. Jebeili, V. Fragomeli, Y. Koay, M. Jackson, J. O’Sullivan, M. Weltman, G. McCaughan, E. El-Omar, A. Zekry   +17 more
semanticscholar   +1 more source