Results 11 to 20 of about 6,127,399 (262)

Relationship Between Nonalcoholic Fatty Liver Disease and Severity of Coronary Artery Disease in Patients Undergoing Coronary Angiography

open access: yesArchives of Basic and Clinical Research
Objective: Nonalcoholic fatty liver disease has been connected to coronary artery disease, which is the main cause of mortality. The connection between the degree of nonalcoholic fatty liver disease-induced liver fibrosis and the severity of coronary ...
Tayyip İlker Aydın   +3 more
doaj   +2 more sources

Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]

open access: yes, 2010
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E.   +70 more
core   +1 more source

Adipokines and redox signaling: impact on fatty liver disease. [PDF]

open access: yes, 2011
Adipokines (adipose tissue cytokines) are polypeptide factors secreted by adipose tissue in a highly regulated manner. The 'classical' adipokines (leptin, adiponectin, and resistin) are expressed only by adipocytes, but other adipokines have been shown ...
Marra, Fabio.   +2 more
core   +1 more source

The global fatty liver disease Sustainable Development Goal country score for 195 countries and territories

open access: yes, 2023
: Background and Aims: Fatty liver disease is highly prevalent, resulting in overarching wellbeing and economic costs. Addressing it requires comprehensive and coordinated multisectoral action.
Buendía Rodríguez, Jefferson Antonio
core   +1 more source

Gut metabolomics and 16S rRNA sequencing analysis of the effects of arecoline on non-alcoholic fatty liver disease in rats

open access: yesFrontiers in Pharmacology, 2023
Introduction: Non-alcoholic fatty liver disease (NAFLD) has gradually become the primary cause of fatty liver disease. Betel nuts have been used to treat gastrointestinal diseases.Methods: In the present study, we analyzed the pathology, serology, gut ...
Lingping Zhu   +4 more
doaj   +1 more source

Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease [PDF]

open access: yes, 2011
The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is associated with delayed histological progression of nonalcoholic fatty liver disease (NAFLD).
Gastaldelli, Amalia   +80 more
core   +1 more source

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]

open access: yes, 2011
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar   +21 more
core   +1 more source

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]

open access: yes, 2011
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...
Palmer Cameron D.   +803 more
core   +5 more sources

Non-alcoholic fatty liver disease: a global concern

open access: yes, 2022
Liver disease is a worldwide issue with death rates exponentially increasing over the last 50 years. Although there are many underlying aetiologies, one of the top three causes of liver disease is non-alcoholic fatty liver disease (NAFLD), which is an ...
Mortimore, G.
core   +1 more source

Comparative efficacy and safety of different regimens of ranibizumab for neovascular age-related macular degeneration: a network meta-analysis of randomised controlled trials

open access: yesBMJ Open, 2021
Objective To give a comprehensive efficacy and safety ranking of different therapeutic regimens of ranibizumab for neovascular age-related macular degeneration (nAMD).Design A systematic review and network meta-analysis.Methods The PubMed, Embase ...
Youxin Chen, Xinyu Zhao, Lihui Meng
doaj   +1 more source

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