Results 51 to 60 of about 129,916 (306)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A new fault tolerant control scheme for non‐linear systems by T‐S fuzzy model approach

open access: yesIET Control Theory & Applications, 2021
This paper is concerned with the problem of fault tolerant control for non‐linear systems with sensor faults based on the T‐S fuzzy model approach. First, a fault estimation (FE) observer with L∞ technique is designed to estimate the fault.
Yue Wu   +3 more
doaj   +1 more source

Fault-tolerant control of a hydraulic servo actuator via adaptive dynamic programming

open access: yesMathematical Modelling and Control, 2023
The fault-tolerant control problem of a hydraulic servo actuator in the presence of actuator faults is studied utilizing adaptive dynamic programming.
Vladimir Stojanovic
doaj   +1 more source

"Intelligent" controllers on cheap and small programmable devices [PDF]

open access: yes, 2013
It is shown that the "intelligent" controllers which are associated to the recently introduced model-free control synthesis may be easily implemented on cheap and small programmable devices.
Chaxel, Frédéric   +2 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Fault estimation and fault-tolerant control for discrete-time dynamic systems [PDF]

open access: yes, 2015
In this paper, a novel discrete-time estimator is proposed, which is employed for simultaneous estimation of system states, and actuator/sensor faults in a discrete-time dynamic system.
Gao, Zhiwei
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Review of Fault-Tolerant Control Methods for Suspension Systems: From Road Vehicles to Maglev Trains

open access: yesMathematics
Road vehicles and maglev trains have garnered significant attention, with their suspension systems being crucial for safe and stable performance. However, these systems can be compromised by faults such as sensor and actuator failures, posing risks to ...
Fei Ni   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

On fault tolerant control structures incorporating fault estimation

open access: yesArchives of Control Sciences, 2016
The paper provides the minimal necessary modifications of linear matrix inequality conditions for the mixed H2/H∞ control design as well as for the augmented observer-based fault estimation to be mutually compatible in joint design of integrated fault ...
Krokavec Dušan   +2 more
doaj   +1 more source

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