Results 51 to 60 of about 6,402 (218)

Adaptive Integral-Type Terminal Sliding Mode Fault Tolerant Control for Spacecraft Attitude Tracking

IEEE Access, 2019
In this paper, the attitude tracking control for a spacecraft system based on a novel adaptive integral-type terminal sliding mode fault-tolerant control strategy is investigated.
Zhao Wang, Qi Li, Shurong Li
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Open-Switch Fault Diagnosis Algorithm and Tolerant Control Method of the Three-Phase Three-Level NPC Active Rectifier

Energies, 2019
This paper proposes a fault diagnosis and tolerant control methods for an open-switch fault caused in a three-phase three-level neutral-point-clamped (NPC) pulse-width modulation (PWM) active rectifier. The open-switch fault in the three-level NPC active
Jun-Hyung Jung, Hyun-Keun Ku, Yung-Deug Son, Jang-Mok Kim   +3 more
doaj   +1 more source

Fault tolerant control in an unmanned bicycle robot via sliding mode theory

IET Cyber-systems and Robotics, 2022
In this work, a new active fault tolerant control (FTC) is developed for an unmanned bicycle robot based on an integration between a sliding mode control (SMC), fault detection (FD), and fault estimation (FE) via a residual signal.
Mousa Alizadeh, Amin Ramezani, Hadis Saadatinezhad   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Fault-Tolerant Model Predictive Control for Autonomous Underwater Vehicles Considering Unknown Disturbances

Journal of Marine Science and Engineering
This paper presents a fault-tolerant model predictive control approach for cross-rudder autonomous underwater vehicles to achieve heading control, considering rudder stuck faults and unknown disturbances.
Yimin Chen, Shaowen Hao, Jian Gao, Jiarun Wang, Le Li   +4 more
doaj   +1 more source

Fault Diagnosis and Fault-Tolerant Control Scheme for Quadcopter UAVs with a Total Loss of Actuator

Energies, 2019
Fault-tolerant control has drawn attention in recent years owning to its reliability and safe flight during missions. In this article, an active fault-tolerant control method is proposed to control a quadcopter in the presence of actuator faults and ...
Ngoc Phi Nguyen, Sung Kyung Hong
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Fault-Tolerant Adaptive Control for a Class of Nonlinear Systems With Uncertain Parameters and Unknown Control Directions

IEEE Access, 2019
This paper investigates the adaptive fault-tolerant control problem for a class of nonlinear systems with unknown control directions and uncertain parameters.
Wenhui Liu, Baoping Ma, Junwei Lu, Fei Xie   +3 more
doaj   +1 more source