Results 61 to 70 of about 129,916 (306)

Fault tolerant model predictive control of open channels [PDF]

, 2014
Automated control of water systems (irrigation canals, navigation canals, rivers etc.) relies on the measured data. The control action is calculated, in case of feedback controller, directly from the on-line measured data.
Blesa Izquierdo, Joaquim, Chuquet, Karine, Duviella, Eric, Horváth, Klaudia   +3 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Attitude Fault-Tolerant Control of Aerial Robots with Sensor Faults and Disturbances

Drones, 2023
In this paper, sensor fault diagnosis and fault tolerant control strategy are investigated for quadcopters under sensor faults and disturbances. We propose the fault diagnosis estimation system and the fault-tolerant control (FTC) method.
Ngoc-P. Nguyen, Phongsaen Pitakwatchara
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Open-Switch Fault Diagnosis Algorithm and Tolerant Control Method of the Three-Phase Three-Level NPC Active Rectifier

Energies, 2019
This paper proposes a fault diagnosis and tolerant control methods for an open-switch fault caused in a three-phase three-level neutral-point-clamped (NPC) pulse-width modulation (PWM) active rectifier. The open-switch fault in the three-level NPC active
Jun-Hyung Jung, Hyun-Keun Ku, Yung-Deug Son, Jang-Mok Kim   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Flatness-based fault tolerant control

Dyna, 2014
Este artículo presenta un método de control tolerante a fallas para sistemas no lineales planos. Las propiedades intrínsecas d e los sistemas planos generan redundancia analítica y permiten calcular todos los estados y las entradas de control del sistema.
César Martínez-Torres, Loïc Lavigne, Franck Cazaurang, Efraín Alcorta-García, David A. Díaz-Romero   +4 more
doaj  

Active actuator fault-tolerant control of a wind turbine benchmark model [PDF]

, 2014
This paper describes the design of an active fault-tolerant control scheme that is applied to the actuator of a wind turbine benchmark. The methodology is based on adaptive filters obtained via the nonlinear geometric approach, which allows to obtain ...
Baldi, Blanke, Bonfè, Castaldi, Chen, De Persis, Ding, Dodson, Edwards, Edwards, Edwards, Edwards, Ioannou, Isermann, Johnson, Mahmoud, Mattone, Odgaard, Odgaard, Odgaard, Odgaard, Rotondo, Sami, Simani, Simani, Simani, Zhang   +26 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Fault Diagnosis and Fault-Tolerant Control Scheme for Quadcopter UAVs with a Total Loss of Actuator

Energies, 2019
Fault-tolerant control has drawn attention in recent years owning to its reliability and safe flight during missions. In this article, an active fault-tolerant control method is proposed to control a quadcopter in the presence of actuator faults and ...
Ngoc Phi Nguyen, Sung Kyung Hong
doaj   +1 more source