Results 71 to 80 of about 129,916 (305)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Fault-Tolerant Adaptive Control for a Class of Nonlinear Systems With Uncertain Parameters and Unknown Control Directions

IEEE Access, 2019
This paper investigates the adaptive fault-tolerant control problem for a class of nonlinear systems with unknown control directions and uncertain parameters.
Wenhui Liu, Baoping Ma, Junwei Lu, Fei Xie   +3 more
doaj   +1 more source

Fault tolerant control in an unmanned bicycle robot via sliding mode theory

IET Cyber-systems and Robotics, 2022
In this work, a new active fault tolerant control (FTC) is developed for an unmanned bicycle robot based on an integration between a sliding mode control (SMC), fault detection (FD), and fault estimation (FE) via a residual signal.
Mousa Alizadeh, Amin Ramezani, Hadis Saadatinezhad   +2 more
doaj   +1 more source

Integrated Sensor Fault Diagnosis and Fault-Tolerant Control for Manipulator [PDF]

, 2019
In this paper, an integrated scheme including fault diagnosis and fault-tolerant controller design is proposed for the manipulator system with the sensor fault. Any constant fault or time-varying fault can be estimated by the fault diagnosis scheme based
Gao, Zhiwei, Hong, Bowen, Yao, Lina
core   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Fault-Tolerant Model Predictive Control for Autonomous Underwater Vehicles Considering Unknown Disturbances

Journal of Marine Science and Engineering
This paper presents a fault-tolerant model predictive control approach for cross-rudder autonomous underwater vehicles to achieve heading control, considering rudder stuck faults and unknown disturbances.
Yimin Chen, Shaowen Hao, Jian Gao, Jiarun Wang, Le Li   +4 more
doaj   +1 more source

Finite-Time Fault-Tolerant Control for a Robot Manipulator Based on Synchronous Terminal Sliding Mode Control

Applied Sciences, 2020
In this paper, two finite-time active fault-tolerant controllers for a robot manipulator, which combine a synchronous terminal sliding mode control with an extended state observer, are proposed.
Quang Dan Le, Hee-Jun Kang
doaj   +1 more source

Electromagnetic design of a new hybrid-excited flux-switching machine for fault-tolerant operations [PDF]

, 2015
Paper no. YD-011541In this paper, a new hybrid-excited flux-switching (HEFS) machine is proposed with the outer-rotor configuration, which possesses the distinct feature of fault-tolerant operation.
Chau, KT, Lin, F, Liu, C, Liu, CH, Qiu, C   +4 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Stator-flux-oriented fault-tolerant control of flux-switching permanent-magnet motors [PDF]

, 2011
Flux-switching permanent-magnet (FSPM) motors are a newly developed brushless AC (BLAC) machine having magnets in the stator. This paper proposes and implements a stator-flux-oriented (SFO) control strategy for fault-tolerant operation of FSPM motors ...
Chau, KT, Cheng, M, Hua, W, Ji, J, Jia, H, Li, W, Zhao, W   +6 more
core   +1 more source