Results 31 to 40 of about 6,140 (133)

Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment

open access: yesFrontiers in Immunology, 2018
The neonatal Fc receptor (FcRn) is responsible for the recycling and transcytosis of IgG and albumin. FcRn level was found altered in cancer tissues and implicated in tumor immunosurveillance and neoplastic cell growth.
Diana Cadena Castaneda   +23 more
doaj   +1 more source

Y$^2$-Net FCRN for Acoustic Echo and Noise Suppression [PDF]

open access: yesarXiv, 2021
In recent years, deep neural networks (DNNs) were studied as an alternative to traditional acoustic echo cancellation (AEC) algorithms. The proposed models achieved remarkable performance for the separate tasks of AEC and residual echo suppression (RES). A promising network topology is a fully convolutional recurrent network (FCRN) structure, which has
arxiv  

Evidenciação de práticas de responsabilidade socioambiental pelas empresas de energia elétrica à luz da NBC T 15

open access: yesRevista Fatec Zona Sul, 2020
Este artigo objetivou analisar a evidenciação de informações socioambientais das empresas de energia elétrica listadas no Índice de Sustentabilidade Empresarial (ISE), com base na NBC T 15.
Jerferson Freitas da Silva   +2 more
doaj  

Bandwidth-Scalable Fully Mask-Based Deep FCRN Acoustic Echo Cancellation and Postfiltering [PDF]

open access: yesarXiv, 2022
Although today's speech communication systems support various bandwidths from narrowband to super-wideband and beyond, state-of-the art DNN methods for acoustic echo cancellation (AEC) are lacking modularity and bandwidth scalability. Our proposed DNN model builds upon a fully convolutional recurrent network (FCRN) and introduces scalability over ...
arxiv  

Deep Noise Suppression With Non-Intrusive PESQNet Supervision Enabling the Use of Real Training Data [PDF]

open access: yesarXiv, 2021
Data-driven speech enhancement employing deep neural networks (DNNs) can provide state-of-the-art performance even in the presence of non-stationary noise. During the training process, most of the speech enhancement neural networks are trained in a fully supervised way with losses requiring noisy speech to be synthesized by clean speech and additive ...
arxiv  

Efficient Acoustic Echo Suppression with Condition-Aware Training [PDF]

open access: yesarXiv, 2023
The topic of deep acoustic echo control (DAEC) has seen many approaches with various model topologies in recent years. Convolutional recurrent networks (CRNs), consisting of a convolutional encoder and decoder encompassing a recurrent bottleneck, are repeatedly employed due to their ability to preserve nearend speech even in double-talk (DT) condition.
arxiv  

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

open access: yesCells, 2022
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have shown
Anna Zakrzewicz   +10 more
doaj   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Human FcRn Tissue Expression Profile and Half-Life in PBMCs

open access: yesBiomolecules, 2019
System-wide quantitative characterization of human neonatal Fc receptor (FcRn) properties is critical for understanding and predicting human PK (pharmacokinetics) as well as the distribution of mAbs and Fc-fusion proteins using PBPK (physiologically ...
Yao-Yun Fan   +5 more
doaj   +1 more source

Zika Virus Infection and Antibody Neutralization in FcRn Expressing Placenta and Engineered Cell Lines

open access: yesVaccines, 2022
As a developmental toxicant, Zika virus (ZIKV) attacks both the growing nervous system, causing congenital Zika syndrome, and the placenta, resulting in pathological changes and associated adverse fetal outcomes.
Yanqun Xu   +6 more
doaj   +1 more source

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