Results 201 to 210 of about 14,337 (261)

Optimization of cultivation strategies for production of recombinant human papillomavirus type 58 major capsid protein L1 in Hansenula polymorpha. [PDF]

Bioresour Bioprocess
Kopitak N, Phimsen W, Sripui K, Khunsom A, Pongsuwichedsak N, Boontawon T, Theeranan T, Boonchird C, Pongtharangkul T.   +8 more
europepmc   +1 more source

High-Level Secretory Expression of Recombinant Type XVII Human-like Collagen in <i>Komagataella phaffii</i>. [PDF]

Int J Mol Sci
Jia Y, Yue J, Wu W, Zhao W, Hu S, Mei L, Wei P, Lyu C.   +7 more
europepmc   +1 more source

Methanol feeding strategies for high-yield production of a collagen-based protein in Komagataella phaffii. [PDF]

Appl Microbiol Biotechnol
Ebbecke JP, Schlauch D, Güler C, Pirmahboub H, Kara S, Pepelanova I.   +5 more
europepmc   +1 more source

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Fed-batch fermentation for ergosterol production

Process Biochemistry, 2003
Abstract The relationship between the fermentation parameters pH, DO and the concentrations of glucose, biomass and the ergosterol content of Saccharomyces cerevisiae in different fed-batch methods are discussed. Different fed-batch methods including constant feed rate fed-batch, constant glucose concentration fed-batch, exponential fed-batch, DO ...
Hua Gao, Tianwei Tan
exaly   +2 more sources

The control of fed-batch fermentation processes—A survey

Automatica, 1987
A survey of the control of fermentation processes operated in fed-batch mode is presented. Truely optimal conditions can only be found by minimizing (or maximizing) a cost criterion subject ot the constraints imposed by a mathematical model of the process.
exaly   +2 more sources

Control of fed-batch fermentations

Biotechnology Advances, 1999
Fed-batch fermentation is used to prevent or reduce substrate-associated growth inhibition by controlling nutrient supply. Here we review the advances in control of fed-batch fermentations. Simple exponential feeding and inferential methods are examined, as are newer methods based on fuzzy control and neural networks.
Lee, J, Lee, SY Lee, SangYup, Park, S Park, Sunwon, Middelberg, APJ   +3 more
openaire   +5 more sources

Calorimetric control of fed‐batch fermentations

Biotechnology and Bioengineering, 1990
AbstractMeasurements of the heat produced by Saccharomyces cerevisiae CBS 426 were used in conjunction with elemental and enthalpic balances to control fed‐batch fermentations. A proportional control using the ratio of carbon dioxide evolution rate to heat production resulted in high biomass yields and minimal ethanol production.
Randolph, T. W., Marison, I. W., Martens, D. E., Von Stockar, U.   +3 more
openaire   +4 more sources

Feedback optimization of fed‐batch fermentation

Biotechnology and Bioengineering, 1987
AbstractThe problem of feedback optimization of the feed rate for fed‐batch fermentation processes is formulated in the framework of singular control theory and switching hypersurfaces. Using four differential balance equations that describe a general class of fedbatch processes and a general objective function to be minimized, it is shown that under ...
J M, Modak, H C, Lim
openaire   +2 more sources

Supervision of fed-batch fermentations

Chemical Engineering Journal, 1999
Process faults may be detected on-line using existing measurements based upon modelling that is entirely data driven. A multivariate statistical model is developed and used for fault diagnosis of an industrial fed-batch fermentation process. Data from several (25) batches are used to develop a model for cultivation behaviour.
Lars Gregersen, Sten Bay Jørgensen
openaire   +1 more source

Reachability of nonlinear fed‐batch fermentation processes

International Journal of Robust and Nonlinear Control, 2002
AbstractThe reachability of a simple nonlinear fed‐batch fermentation process model is investigated in this paper. It is shown that the known difficulties of controlling such processes are primarily caused by the fact that the rank of the reachability distribution is always less than the number of state variables.Furthermore, a co‐ordinates ...
Szederkényi, G., Kovács, M., Hangos, K. M.   +2 more
openaire   +2 more sources