Results 221 to 230 of about 14,337 (261)

Ammonium controlled fed-batch fermentation for amylase production

Journal of Fermentation and Bioengineering, 1989
Abstract Batch and ammonium controlled fed-batch fermentations were compared for the production of amylase by Bacillus amyloliquefaciens . In shake flask culture, maximum amylase production was obtained when the concentration of ammonium was 20–30 mM. In a 15 l batch fermentation, maximum amylase production occurred at an ammonium concentration of
Manoj M. Kole, Donald F. Gerson
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Optimal nonsingular control of fed‐batch fermentation

Biotechnology and Bioengineering, 1991
AbstractPresented is a new simple method for multidimensional optimization of fed‐batch fermentations based on the use of the orthogonal collocation technique. Considered is the problem of determination of optimal programs for fermentor temperature, substrate concentration in feed, feeding profile, and process duration.
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Fault detection and diagnosis in industrial fed-batch fermentation

2006 American Control Conference, 2006
This paper applies multivariate statistical process control (MSPC) techniques to pilot plant fermentation data for the purpose of fault detection and diagnosis. Data from ten batches, nine normal operating conditions (NOC) and one failed, were available.
Jon C. Gunther, Dale E. Seborg, Jeffrey Baclaski   +2 more
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Fed-batch versus batch fermentation

Bioprocess Engineering, 1994
This article concerns the comparison between batch and fed-batch fermentation based on productivity and including the analysis of the implications on product manufacturing cost.
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Fed-batch fermentation controller design with evolutionary computation

Proceedings of the 5th international conference on Soft computing as transdisciplinary science and technology - CSTST '08, 2008
In this paper the controllers for the benchmark fed-batch fermentation process are obtained using the method of interactive evolutionary computation (IEC). The results allow us to conclude that IEC is a viable and very effective alternative to existing methods if the eventual solution is expected to be relatively simple (so it can be found with ...
Andri Riid, Ennu Rüstern
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Rational Design and Optimization of Fed-Batch and Continuous Fermentations

2007
This chapter provides rational approaches to design and optimize fed-batch and continuous fermentations of both Mut+ and Muts (methanol utilization plus and slow) Pichia pastoris strains. The methods are described in detail for glycerol batch, glycerol fed-batch, transition, and methanol fed-batch/mixed feed/ continuous stirred tank reactor (CSTR ...
Wenhui, Zhang, Mehmet, Inan, Michael M, Meagher   +2 more
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Principles and Case Studies of Fed Batch Fermentation and Continuous Fermentation

Journal of Clinical and Nursing Research, 2022
Modern fermentation processes include a variety of fermentation methods, such as fed batch fermentation and continuous fermentation. This paper will focus on the principles and case studies of these two methods. Fed batch fermentation originates from fractionation fermentation with closed culture and adjustment of the pH value of the carbon source, to ...
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Effects of mixing on fed-batch fermentation of l-ornithine

Journal of Bioscience and Bioengineering, 2000
The effects of mixing on L-ornithine fermentation were studied using an L-arginine auxotrophic mutant of Brevibacterium ketoglutamicum ATCC 21092. Three different modes of fed-batch culture using two different impeller types were studied in a 7 l fermentor.
H, Lee, S, Yoon, H, Jang, C, Kim, T, Kim, W, Ryu, J, Jung, Y, Park   +7 more
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Optimal switching control of a fed-batch fermentation process

Journal of Global Optimization, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chongyang Liu, Zhaohua Gong, Enmin Feng, Hongchao Yin   +3 more
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Evaluation of spectrofluorometry as a tool for estimation in fed‐batch fermentations

Biotechnology and Bioengineering, 2003
AbstractNative culture fluorescence was investigated as an additional source of information for predicting biomass and glucose concentrations in a fed‐batch fermentation of Alcaligenes eutrophus. Partial least squares (PLS) regression and a feed forward neural network (FFNN) coupled with principle component analysis (PCA) were each used to model the ...
Andrea, Hagedorn, Raymond L, Legge, Hector, Budman   +2 more
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