Results 41 to 50 of about 1,419,151 (290)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phrasing Feedback to Improve Students' Writing in a Large First-Year Humanities Course

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2021
On a revise-and-resubmit assignment in a large introductory History course, students were provided with feedback that was phrased either as questions, statements, or imperatives.
Mairi Cowan   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

O conceito de relevância e o feedback do usuário final do Repositório Institucional da Universidade de Brasília

open access: yesRevista Ibero-Americana de Ciência da Informação, 2012
Apresenta estudo sobre a relevância adotada pelo Repositório Institucional da Universidade de Brasília e o feedback do usuário às respostas de recuperação da informação.
Carlos Duarte Oliveira Junior   +3 more
doaj  

Sistemic Approach - a Complexity Management Instrument [PDF]

open access: yesTheoretical and Applied Economics, 2006
he systemic principle uses the deduction and the induction, analyse and synthesis, inferency and proferency, in order to find out the interdependencies and the inner connections that make mooving the complex organized entities.
Vadim Dumitrascu
doaj  

Patient involvement in developing a patient‐targeted feedback intervention after depression screening in primary care within the randomized controlled trial GET.FEEDBACK.GP

open access: yesHealth Expectations, 2021
Background Patient and public involvement (PPI) is increasingly required in mental health services research. To empower patients to actively address depression, the GET.FEEDBACK.GP study evaluates a patient‐targeted feedback intervention after depression
Tharanya Seeralan   +12 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Treating Eating: A Dynamical Systems Model of Eating Disorders

open access: yesFrontiers in Psychology, 2020
Mainstream forms of psychiatric talk therapy and cognitive behavioral therapy (CBT) do not reliably generate lasting recovery for eating disorders. We discuss widespread assumptions regarding the nature of eating disorders as fundamentally psychological ...
Emily T. Troscianko, Michael Leon
doaj   +1 more source

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