Results 91 to 100 of about 86,514 (304)

Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne

Drug Testing and Analysis, EarlyView.
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku, Anna Pelander, Antti Jylhä, Ilkka Ojanperä   +3 more
wiley   +1 more source

Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]

, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

Drug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke, Florian Zapf, Tanja Restin, Thomas Kraemer, Tina M. Binz   +4 more
wiley   +1 more source

Anesthetic Induction with Fentanyl

Survey of Anesthesiology, 1985
The efficacy of fentanyl, 30 micrograms/kg, was evaluated as an anesthetic induction agent in 72 ASA I-III patients scheduled for 2-4-hr operations. The effect of preinduction pretreatment with pancuronium and/or diazepam and the incidence of loss of consciousness (anesthesia), recall, rigidity, abnormal muscle movements, and hemodynamic changes were ...
Johan Wilbrink, Nathan L. Pace, Peter L. Bailey, Prisca Zwanikken, Theodore H. Stanley   +4 more
openaire   +3 more sources

Hidden Costs of Ban the Box Laws: Unraveling the Effects on Drug‐Related Deaths

Health Economics, EarlyView.
ABSTRACT Ban the Box (BTB) laws delay criminal background checks until the later stages of the hiring process. This study provides new evidence that BTB laws that apply to both private and public employers have negative spillover effects beyond labor market outcomes.
Oleksandra Cheipesh
wiley   +1 more source

Intraoperative Isoflurane End-Tidal Concentration during Infusion of Fentanyl, Tramadol, or Fentanyl–Tramadol Combination in Cats

Veterinary Sciences
The aim of this study was to evaluate the end-tidal concentration of isoflurane required, clinical parameters, intraoperative antinociceptive effect, and postoperative analgesia in cats undergoing ovariohysterectomy, receiving fentanyl, tramadol, or ...
Claudia Interlandi, Fabio Bruno, Marco Tabbì, Francesco Macrì, Simona Di Pietro, Elisabetta Giudice, Patrizia Licata, Daniele Macrì, Viola Zappone, Giovanna Lucrezia Costa   +9 more
doaj   +1 more source

Butorphanol for Post-Operative Analgesia - A Comparative Clinical Study with Ketorolac [PDF]

, 2010
Introduction: Butorphanol, an opioid derivative has been shown to have, in addition to its analgesic properties, several other advantageous effects like antistressor, sedative and anti-shivering action.
Adappa, Karunakara, Kadam, Dinesh, Kadri, Rajani, Koteshwar, Reshma, Mohan, Prashanth, Shenoy, Sunil P, Tantry, Thrivikrama Padur, Vastrad, Nandish S   +7 more
core   +1 more source

Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance in male and female mice

Addiction Neuroscience
The number of opioid overdose deaths has increased over the past several years, mainly driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the un-regulated drug supply.
Anthony M. Downs, Gracianne Kmiec, Zoé A. McElligott   +2 more
doaj   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone

Toxics
Opioid-related deaths are attributed to overdoses, and fentanyl overdose has been on the rise in many parts of the world, including the USA. Glutamate transporter 1 (GLT-1) has been identified as a therapeutic target in several preclinical models of ...
Mohammed S. Alasmari, Fawaz Alasmari, Shakir D. Alsharari, Abdullah F. Alasmari, Nemat Ali, Syed Rizwan Ahamad, Abdullah M. Alghamdi, Aban A. Kadi, Alaa M. Hammad, Yousif S. Mohamed Ali, Wayne E. Childers, Magid Abou-Gharbia, Youssef Sari   +12 more
doaj   +1 more source