Results 91 to 100 of about 195,889 (397)

Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal [PDF]

, 2018
This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with
Clark, Peter, Cooney, Kevin, DiMeglio, M., Dubensky, J., Gulati, S., Lathrop, S., Lee, Marvin J. H., Minupuri, A., Nguyen, Olivia, Patel, P., Schadt, Sam A., Umapathy, S., Zheng, S.   +12 more
core  

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Fentanyl and its derivatives: Pain-killers or man-killers?

Heliyon
Fentanyl is a synthetic μ-opioid receptor agonist approved to treat severe to moderate pain with faster onset of action and about 100 times more potent than morphine.
Jiri Patocka, Wenda Wu, Patrik Oleksak, Romana Jelinkova, Eugenie Nepovimova, Lenka Spicanova, Pavlina Springerova, Suliman Alomar, Miao Long, Kamil Kuca   +9 more
doaj   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Effects of intrathecal opioids use in cesarean section on breastfeeding and newborns’ weight gaining [PDF]

, 2016
Objective: To assess the association between intrapartum intrathecal opioid use and breastfeeding and weight gain following cesarean section. Materials and methods: The prospective double-blinded study was conducted on term pregnant women, undergoing ...
Anbarafshan, Mohammad, Davari-Tanha, Fatemeh, Kaveh, Mahbod, Khashayar, Patricia, Najafi, Atabak, Rezaei Hemami, Mohsen, Yousefshahi, Fardin   +6 more
core   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]

, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Fentanyl self-testing outside supervised injection settings to prevent opioid overdose: Do we know enough to promote it? [PDF]

, 2018
Since 2013, North America has experienced a sharp increase in unintentional fatal overdoses: fentanyl, and its analogues, are believed to be primarily responsible.
Australian Injecting & Illicit Drug Users League, Catherine R. McGowan, Centers for Disease Control and Prevention, Ciccarone, Ciccarone, Ciccarone, Clark, Compton, Cressman, Daniulaityte, European Monitoring Centre for Drugs and Drug Addiction, Fairbairn, Frank, Friedman, Gladden, Harris, Human Rights Watch, Johns Hopkins Bloomberg School of Public Health, Jozaghi, Lucy Platt, Lysyshyn, Magdalena Harris, Marshall, Massey, McGowan, Messac, Mounteney, Murray, Neira-Leon, O'Donnell, Quest, Rhodes, Rhodes, Rhodes, Rhodes, Schneider, Seth, Shaheen, Socias, Stewart, The Vancouver Sun, Tim Rhodes, United Nations Office on Drugs and Crime, United States Drug Enforcement Administration, United States Drug Enforcement Administration, Vivian Hope, Winstock   +46 more
core   +2 more sources

Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne

Drug Testing and Analysis, EarlyView.
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku, Anna Pelander, Antti Jylhä, Ilkka Ojanperä   +3 more
wiley   +1 more source

Fentanyl and Fentanyl Subgroups as Chemical Weapons

Hacettepe Journal of Biology and Chemistry
2002 yılında Rusya’nın Başkenti Moskova’daki bir tiyatronun Çeçen işgalcilercelerce ele geçirilmesi neticesinde yapılan rehine kurtarma operasyonunda işgalciler de dahil olmak üzere 130 kişi hayatını kaybetmiştir. Bu operasyonda güvenlik güçlerince kullanılan remifentanil ve karfentaniller, Kimyasal Silahlar Sözleşmesince, Kimyasal Silah olarak ...
Caner Dereli, Nebile Dağlıoğlu
openaire   +2 more sources