Results 61 to 70 of about 195,889 (397)
Journal of Neuroscience, 2020 We recently developed a rat model of relapse to drug seeking after food choice-induced voluntary abstinence. Here, we used this model to study the role of the orbitofrontal cortex (OFC) and its afferent projections in relapse to fentanyl seeking.
D. Reiner +7 more
semanticscholar +1 more source
BMC Global and Public HealthBackground In the USA, many states, including Colorado, have increased criminal penalties for illicit opioid possession, which may alter overdose risk.
Katherine LeMasters +10 more
doaj +1 more source
MMWR. Morbidity and mortality weekly report, 2020 Approximately two thirds of the 70,237 U.S. drug overdose deaths reported in 2017 involved opioids (1). Since 2013, opioid-involved overdose deaths involving illicitly manufactured fentanyl has sharply increased (1,2).
J. O'Donnell +4 more
semanticscholar +1 more source
Qualitative identification of fentanyl and other synthetic opioids using ambient ionization high resolution time-of-flight mass spectrometry [PDF]
, 2017 The Centers for Disease Control and Prevention deemed the increase in overdose fatalities, due to the use of opioids, an “opioid epidemic” in the United States. Heroin, fentanyl, and other synthetic opioids are commonly abused and are contributing to the
Moore, Amanda Marie
core
Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? [PDF]
, 2015 © 2015, BMJ Publishing Group. All rights reserved. Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this
Currow, David C. +10 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Journal of Pharmacology and Experimental Therapeutics, 2020 Synthetic opioids, including fentanyl and its analogs, have therapeutic efficacy in analgesia and anesthesia. However, their illicit use in the United States has increased and contributed to the number one cause of death for adults 18–50 years old ...
Randy Torralva +8 more
semanticscholar +1 more source
Advanced Sensor Research, EarlyView.A foam‐based ELISA (f‐ELISA) platform was developed using chemically modified melamine foam to enable rapid, ultrasensitive, and selective colorimetric detection of fentanyl and norfentanyl. Abstract Rapid and accurate detection of fentanyl in unknown products and aqueous samples can find the unexpected existence of the toxic chemical and assist law ...
Makela Norwood, Bofeng Pan, Gang Sun
wiley +1 more source
Fentanyl demand and seeking in female rats: Role of the orexin system and estrous cycle
Addiction NeuroscienceThe orexin system plays a major role in drug reward. Orexin-1 receptor (OxR1) blockade reduces fentanyl demand in males. However, there are a number of sex differences in the orexin system, and it is unclear how OxR1 antagonism would decrease fentanyl ...
David De Sa Nogueira +6 more
doaj +1 more source
Characteristics of Fentanyl Overdose — Massachusetts, 2014–2016
MMWR. Morbidity and mortality weekly report, 2017 Opioid overdose deaths in Massachusetts increased 150% from 2012 to 2015 (1). The proportion of opioid overdose deaths in the state involving fentanyl, a synthetic, short-acting opioid with 50-100 times the potency of morphine, increased from 32% during ...
Nicholas J. Somerville +12 more
semanticscholar +1 more source