Results 101 to 110 of about 5,252 (212)
Journal of Biophotonics, Volume 19, Issue 5, May 2026.This study demonstrates that 5‐ALA BL PDT induces greater levels of apoptosis in SCC cells in a wavelength‐, 5‐ALA dose‐, and temperature‐dependent manner, compared to 5‐ALA RL PDT, with higher concentrations of ALA and elevated temperatures stimulating the greatest apoptotic activity.
Julia Stolyar +5 more
wiley +1 more source
Cell modeling of heme deficiency using ferrochelatase mutations
, 2014 Provided herein, is a means for development of ferrochelatase variants with improved tolerance towards N-methyl protoporphyrin. Also disclosed are cell assay systems utilizing the variants, as the variants would confer resistance to N-methyl ...
Ferreira, Gloria C., Shi, Zhen
core
The coding sequence of the bovine ferrochelatase gene
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1995 The amino acid code and surrounding regions in the bovine ferrochelatase gene were amplified by a combination of reverse transcriptase PCR and vectorette PCR and sequenced. The bovine code was 86% homologous to the human ferrochelatase code but was altered at a position corresponding to the presumed human initiator codon.
Shibuya, Hisashi +4 more
openaire +2 more sources
Modulation of inhibition of ferrochelatase by N-methyl protoporphyrin
, 2013 Provided herein, is a means for development of ferrochelatase variants with improved tolerance towards N-methyl protoporphyrin. Also disclosed are cell assay systems utilizing the variants, as the variants would confer resistance to N-methyl ...
Ferreira, Gloria C., Shi, Zhen
core
Bacterial Porphyrin Extraction and Quantification by LC/MS/MS Analysis
Bio-Protocol, 2015 Heme is an iron-containing porphyrin which acts as a prosthetic group in several enzymes involved in disparate functions, such as respiration and H2O2-scavenging.
Stefano Mancini, James Imlay
doaj +1 more source
, 1977 Regulatory factors affecting ferrochelatase activity were studied and an attempt was made to determine the role of ferrochelatase in the regulation of heme biosynthesis.
Simpson, Denyse Marie
core +1 more source
Yeast Frataxin Solution Structure, Iron Binding, and Ferrochelatase Interaction†,‡
, 2016 The mitochondrial protein frataxin is essential for cellular regulation of iron homeostasis. Although the exact function of frataxin is not yet clear, recent reports indicate the protein binds iron and can act as a mitochondrial iron chaperone to ...
Yan Zhang (8098) +6 more
core +1 more source
Purification and characterisation of a water-soluble ferrochelatase from Bacillus subtilis
, 1994 Bacillus subtilis ferrochelatase is encoded by the hemH gene of the hemEHY gene cluster and catalyses the incorporation of Fe2+ into protoporphyrin IX. B. subtilis ferrochelatase produced in Escherichia coli was purified.
Hederstedt, Lars +4 more
core +1 more source
, 1991 International audienceA viable autosomal recessive mutation (named fch, or ferrochelatase deficiency) causing jaundice and anemia in mice arose in a mutagenesis experiment using ethylnitrosourea.
Rouyer-Fessard, P +20 more
core +1 more source
Factors influencing the stability of heme and ferrochelatase: role of oxygen
, 1991 Ferrochelatase (EC 4.99.1.1) catalyzed heme synthesis is best accomplished in an anaerobic environment. Factors responsible for this phenomenon are not fully understood.
Punekar, N. S., Gokhale, R. S.
core +1 more source