Results 31 to 40 of about 5,252 (212)
Bacterial ferrochelatase turns human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase [PDF]
, 2010 Ferrochelatase catalyzes the insertion of Fe(2+) into protoporphyrin IX. The enzymatic product heme (protoheme IX) is a well-known cofactor in a wide range of proteins.
Salam Al-Karadaghi +35 more
core +1 more source
Agronomy, 2020 We investigated the roles of two Ferrochelatases (FCs), which encode the terminal enzyme for heme biosynthesis, in drought and oxidative stress tolerance in model cereal plant barley (Hordeum vulgare).
Dilrukshi S. K. Nagahatenna +4 more
doaj +1 more source
Ferrochelatase activity of plant frataxin [PDF]
Biochimie, 2019 Frataxin plays a key role in cellular iron homeostasis of different organisms. It is engaged in several activities at the FeS cluster assembly machinery and it is also involved in heme biosynthesis. In plants, two genes encoding ferrochelatases (FC1 and FC2) catalyze the incorporation of iron into protoporphyrin IX in the last stage of heme synthesis ...
Alejandro M. Armas +5 more
openaire +3 more sources
Journal of the Formosan Medical Association, 2014 Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of oral precancerous and cancerous lesions. This in vitro study tried to examine whether the SCC4 cell killing by ALA-PDT was enhanced by pretreatment of ...
Deng-Fu Yang +4 more
doaj +1 more source
Agronomy, 2020 Ferrochelatase (FC) is the terminal enzyme of heme biosynthesis. In photosynthetic organisms studied so far, there is evidence for two FC isoforms, which are encoded by two genes (FC1 and FC2).
Dilrukshi S. K. Nagahatenna +4 more
doaj +1 more source
Redox Biology, 2021 Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the ...
Jonathan V. Dietz +12 more
doaj +1 more source
Ferrochelatase of Rhodopseudomonas spheroides [PDF]
Biochemical Journal, 1970 Extracts of Rhodopseudomonas spheroides contain two ferrochelatases: one is soluble and forms metalloporphyrins from deuteroporphyrin and haematoporphyrin; the other is particulate and forms metalloporphyrins from protoporphyrin, mesoporphyrin, deuteroporphyrin and haematoporphyrin.
M S, Jones, O T, Jones
openaire +2 more sources
Diagnosis and treatment of icteric hepatitis caused by erythropoietic protoporphyria: A case report
Liver Research, 2022 Erythropoietic protoporphyria (EPP) is a rare inherited disease caused by partial deficiency activity of the enzyme ferrochelatase (FECH), resulting in excessive accumulation of protoporphyrin IX in erythrocyte and tissues. Here, we report a patient with
Hanqing Huang +3 more
doaj +1 more source
Ferrochelatase of spinach chloroplasts [PDF]
Biochemical Journal, 1968 Spinach chloroplasts catalyse the incorporation of Fe2+ into protoporphyrin, mesoporphyrin and deuteroporphyrin to form the corresponding haems. This ferrochelatase activity was detected by pyridine haemochrome formation with acetone-dried powders of chloroplasts, or from the formation of [59Fe]haems by intact chloroplasts. Decreasing the mitochondrial
openaire +2 more sources
Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice1
Journal of Lipid Research, 2001 Erythropoietic protoporphyria (EPP) is an inherited disorder of heme synthesis caused by deficiency of the mitochondrial enzyme ferrochelatase. EPP in humans is associated with liver disease, hypertriglyceridemia, and a low level of high density ...
Vincent W. Bloks +9 more
doaj +1 more source