Results 51 to 60 of about 4,023 (167)
Erythropoietic Protoporphyria in a Japanese Population
Acta Dermato-Venereologica, 2019 Erythropoietic protoporphyria is caused by a partial deficiency of ferrochelatase, which is the last enzyme in the heme biosynthesis pathway. In a typical erythropoietic protoporphyria, photosensitivity initially appears, following the first exposure to ...
Megumi Mizawa +4 more
doaj +1 more source
Respirology Case Reports, Volume 14, Issue 8, August 2026.We report a case of chronic myeloid leukaemia (CML) diagnosed during long‐term alectinib therapy in a patient with ALK‐positive non‐small cell lung cancer, in whom CML was confirmed by the presence of the BCR‐ABL1 fusion gene and concomitant nilotinib with continued alectinib achieved a rapid hematologic response without significant adverse events ...
Yuki Ikematsu +3 more
wiley +1 more source
Liver transplantation for acute-on-chronic liver failure from erythropoietic protoporphyria [PDF]
Clinical and Molecular Hepatology, 2012 Erythropoietic protoporphyria (EPP) is an inherited disorder of the heme metabolic pathway that is characterized by accumulation of protoporphyrin in the blood, erythrocytes, and tissues, and cutaneous manifestations of photosensitivity, all resulting ...
Pyoung-Jae Park +9 more
doaj +1 more source
Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy
MedComm – Oncology, Volume 5, Issue 2, June 2026.Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley +1 more source
Disease Models & Mechanisms, 2017 Erythropoietic protoporphyria (EPP) is caused by deficiency of ferrochelatase (FECH), which incorporates iron into protoporphyrin IX (PPIX) to form heme.
Jasmin Barman-Aksözen +9 more
doaj +1 more source
The Journal of Dermatology, Volume 53, Issue 6, Page 930-933, June 2026.ABSTRACT A 50‐year‐old female patient was referred to our department for consultation regarding perioperative management of breast cancer surgery. She had a history of photosensitivity since childhood and was diagnosed with erythropoietic protoporphyria (EPP) during her first pregnancy.
Fumika Tateishi +5 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki +8 more
wiley +1 more source
Effect of Cellular Location on the Function of Ferrochelatase [PDF]
Journal of Biological Chemistry, 1995 Ferrochelatase, the terminal enzyme of the heme biosynthetic pathway, is a nuclear encoded protein that is synthesized in the cytoplasm in a precursor form and then is translocated to the matrix side of the inner mitochondrial membrane. Since the product of the enzymatic reaction, protoheme IX, is utilized almost exclusively in the cytoplasmic ...
A R, Prasad, H A, Dailey
openaire +2 more sources
Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis.
PLoS ONE, 2015 Iron is required as an element to sustain life in all eukaryotes and most bacteria. Although several bacterial iron acquisition strategies have been well explored, little is known about the intracellular trafficking pathways of iron and its entry into ...
Andreas Mielcarek +3 more
doaj +1 more source
Chemical Characterization of Toxic Elements in Plastic Utensils: Key Insights and Health Impacts
CLEAN – Soil, Air, Water, Volume 54, Issue 5, May 2026.Toxic elements in plastic utensils are assessed using portable X‐ray fluorescence and specific migration tests with water and 3% acetic acid as food simulants. Cadmium, lead, arsenic, and mercury are detected in the utensils, and migration results show exceedances of specific migration limits, particularly for lead, mercury, and cadmium. These findings
Elizeu Chiodi Pereira +5 more
wiley +1 more source