Results 71 to 80 of about 4,023 (167)

Infrared Photobiomodulation Modulates PpIX Production After Topical Methyl Aminolevulinate in Normal Human Skin: An Exploratory Study

open access: yesJournal of Biophotonics, Volume 19, Issue 3, March 2026.
We demonstrate that NIR photobiomodulation can influence PpIX accumulation in normal human skin. Although subject to interindividual variability, the observed trends support PBM as a promising, noninvasive adjuvant to refine PDT protocols and manage photosensitizer production through mitochondrial stimulation.
Letícia Palombo Martinelli   +4 more
wiley   +1 more source

A model for tetrapyrrole synthesis as the primary mechanism for plastid-to-nucleus signaling during chloroplast biogenesis

open access: yesFrontiers in Plant Science, 2013
Chloroplast biogenesis involves the co-ordinated expression of the chloroplast and nuclear genomes, requiring information to be sent from the developing chloroplasts to the nucleus.
Matthew J. Terry   +2 more
doaj   +1 more source

Engineering next‐generation crops through CRISPR‐mediated horizontal gene transfer

open access: yesNew Phytologist, Volume 249, Issue 6, Page 2683-2689, March 2026.
Summary Crops increasingly face overlapping stresses such as heat, drought, salinity, and pathogens that conventional breeding or genome editing rarely overcome in combination. To address this, we propose CRISPR‐enabled horizontal gene transfer (CRISPR‐HGT) as a programmable framework that recreates the evolutionary process by which plants historically
Madhab Kumar Sen   +3 more
wiley   +1 more source

Heme Synthesis Inhibition Blocks Angiogenesis via Mitochondrial Dysfunction

open access: yesiScience, 2020
Summary: The relationship between heme metabolism and angiogenesis is poorly understood. The final synthesis of heme occurs in mitochondria, where ferrochelatase (FECH) inserts Fe2+ into protoporphyrin IX to produce proto-heme IX.
Trupti Shetty   +4 more
doaj   +1 more source

Transcriptional regulation of tetrapyrrole biosynthetic genes explains abscisic acid-induced heme accumulation in the unicellular red alga Cyanidioschyzon merolae

open access: yesFrontiers in Plant Science, 2016
Abscisic acid (ABA), a pivotal phytohormone that is synthesized in response to abiotic stresses and other environmental changes, induces various physiological responses. Heme, in its unbound form, has a positive signaling role in cell-cycle initiation in
Yuki Kobayashi, Kan Tanaka, Kan Tanaka
doaj   +1 more source

The coding sequence of the bovine ferrochelatase gene

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1995
The amino acid code and surrounding regions in the bovine ferrochelatase gene were amplified by a combination of reverse transcriptase PCR and vectorette PCR and sequenced. The bovine code was 86% homologous to the human ferrochelatase code but was altered at a position corresponding to the presumed human initiator codon.
Shibuya, Hisashi   +4 more
openaire   +2 more sources

Bacterial Porphyrin Extraction and Quantification by LC/MS/MS Analysis

open access: yesBio-Protocol, 2015
Heme is an iron-containing porphyrin which acts as a prosthetic group in several enzymes involved in disparate functions, such as respiration and H2O2-scavenging.
Stefano Mancini, James Imlay
doaj   +1 more source

Role of Bacterioferritin & Ferritin in M. tuberculosis Pathogenesis and Drug Resistance: A Future Perspective by Interactomic Approach

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Tuberculosis is caused by Mycobacterium tuberculosis, one of the most successful and deadliest human pathogen. Aminoglycosides resistance leads to emergence of extremely drug resistant strains of M. tuberculosis.
Divakar Sharma, Deepa Bisht
doaj   +1 more source

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