Results 61 to 70 of about 4,768 (212)
Chemical Characterization of Toxic Elements in Plastic Utensils: Key Insights and Health Impacts
CLEAN – Soil, Air, Water, Volume 54, Issue 5, May 2026.Toxic elements in plastic utensils are assessed using portable X‐ray fluorescence and specific migration tests with water and 3% acetic acid as food simulants. Cadmium, lead, arsenic, and mercury are detected in the utensils, and migration results show exceedances of specific migration limits, particularly for lead, mercury, and cadmium. These findings
Elizeu Chiodi Pereira +5 more
wiley +1 more source
Effect of Cellular Location on the Function of Ferrochelatase [PDF]
Journal of Biological Chemistry, 1995 Ferrochelatase, the terminal enzyme of the heme biosynthetic pathway, is a nuclear encoded protein that is synthesized in the cytoplasm in a precursor form and then is translocated to the matrix side of the inner mitochondrial membrane. Since the product of the enzymatic reaction, protoheme IX, is utilized almost exclusively in the cytoplasmic ...
A R, Prasad, H A, Dailey
openaire +2 more sources
Disease Models & Mechanisms, 2017 Erythropoietic protoporphyria (EPP) is caused by deficiency of ferrochelatase (FECH), which incorporates iron into protoporphyrin IX (PPIX) to form heme.
Jasmin Barman-Aksözen +9 more
doaj +1 more source
Journal of Biophotonics, Volume 19, Issue 5, May 2026.This study demonstrates that 5‐ALA BL PDT induces greater levels of apoptosis in SCC cells in a wavelength‐, 5‐ALA dose‐, and temperature‐dependent manner, compared to 5‐ALA RL PDT, with higher concentrations of ALA and elevated temperatures stimulating the greatest apoptotic activity.
Julia Stolyar +5 more
wiley +1 more source
Purification and characterization of chicken erythrocyte ferrochelatase [PDF]
Biochemical Journal, 1984 Ferrochelatase (EC 4.99.1.1) was purified 2000-fold to apparent homogeneity from isolated chicken erythrocyte mitochondria. The purified enzyme yields a single band on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis with an apparent Mr of 42 000.
J W, Hanson, H A, Dailey
openaire +2 more sources
Journal of Biological Chemistry, 1994 Ferrochelatase (EC 4.99.1.1) catalyzes the terminal step in the heme biosynthetic pathway, the insertion of ferrous iron into protoporphyrin IX. Herein we report the expression, purification, and characterization of the mature processed form of human and mouse ferrochelatase in Escherichia coli JM109.
H A, Dailey, V M, Sellers, T A, Dailey
openaire +2 more sources
Porphyrin Interactions with Wild Type and Mutant Mouse Ferrochelatase [PDF]
, 1999 Ferrochelatase (EC 4.99.1.1), the terminal enzyme of the heme biosynthetic pathway, catalyzes Fe2+ chelation into protoporphyrin IX. Resonance Raman and W-visible absorbance spectroscopes of wild type and engineered variants of murine ferrochelatase were
Ferreira, Gloria C. +4 more
core
, 1995 The cDNA for human ferrochelatase, the enzyme that is defective in the rare genetic disease erythropoletic protoporphyria (EPP), was tested for its ability to allow the expression of ferrochelatase in mammalian cells.
James L. Michel +5 more
core +1 more source
Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis.
PLoS ONE, 2015 Iron is required as an element to sustain life in all eukaryotes and most bacteria. Although several bacterial iron acquisition strategies have been well explored, little is known about the intracellular trafficking pathways of iron and its entry into ...
Andreas Mielcarek +3 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Lead is a nonessential, toxic heavy metal that causes widespread environmental contamination, affecting humans, animals, plants, and ecosystems. Globally, an estimated 800 million children have blood lead levels (BLLs) above 5 µg/dL.
Gudisa Bereda
wiley +1 more source