Results 101 to 110 of about 12,274 (205)
Potential Usefulness of Urinary Hepcidin Measurement for Iron Deficiency Anemia in Female Athletes
European Journal of Sport Science, Volume 26, Issue 6, June 2026.ABSTRACT Hepcidin is a key regulator of iron metabolism and has been proposed as a biomarker for detecting iron deficiency. This study examined serum hepcidin and non‐invasively measured urinary hepcidin in 260 female athletes to assess their potential utility in evaluating iron status. Urinary hepcidin/creatinine showed a strong correlation with serum
Haruo Hanawa +8 more
wiley +1 more source
HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease
BiomedicinesIron overload can lead to increased deposition of iron and cause organ damage in the liver, the pancreas, the heart and the synovium. Iron overload disorders are due to either genetic or acquired abnormalities such as excess transfusions or chronic liver
Elias Kouroumalis +2 more
doaj +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
MedComm, Volume 7, Issue 6, June 2026.Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Inherited Disorders of Iron Overload
Frontiers in Nutrition, 2018 Dietary iron absorption and systemic iron traffic are tightly controlled by hepcidin, a liver-derived peptide hormone. Hepcidin inhibits iron entry into plasma by binding to and inactivating the iron exporter ferroportin in target cells, such as duodenal
Kostas Pantopoulos, Kostas Pantopoulos
doaj +1 more source
Pediatric Ferroportin Disease [PDF]
Journal of Pediatric Gastroenterology and Nutrition, 2016 Galicia-Poblet, Gonzalo +6 more
openaire +2 more sources
Frontiers in Immunology, 2017 Human lactoferrin (hLf), an 80-kDa multifunctional iron-binding cationic glycoprotein, is constitutively secreted by exocrine glands and by neutrophils during inflammation. hLf is recognized as a key element in the host immune defense system.
Antimo Cutone +7 more
doaj +1 more source
Ferroportin in the progression and prognosis of hepatocellular carcinoma.
European journal of medical research, 2013 Hepatocellular carcinoma (HCC) is the fifth most common malignant tumor in men and the seventh in women and understanding the molecular mechanisms of HCC and establishing more effective therapies are critical and urgent issues. Our objective was to study the expression of ferroportin in hepatocellular carcinoma (HCC) tissue samples and the relationship
Wang, Qin +4 more
openaire +2 more sources
Targeting hepcidin to restore oral iron efficacy after vertical sleeve gastrectomy
Frontiers in NutritionBackgroundMetabolic bariatric surgery (MBS) such as Vertical Sleeve Gastrectomy (VSG) is the most effective intervention for obesity but commonly results in iron deficiency, inadequately managed by oral iron supplementation.
Xiaozhuo Tan +7 more
doaj +1 more source
Hepcidin-mediated ferroportin internalization.
, 2013 Different concentrations of synthetic hepcidin-25, -24, -22 and -20 (indicated in nM on the horizontal axis) were added to the growth medium of a stable cell line that expresses green fluorescent protein-fused ferroportin (GFP-FPN). Hepcidin-mediated GFP-
Hendrik Gille (466748) +7 more
core +1 more source
The determinants of hepcidin‐ferroportin interaction
The FASEB Journal, 2009 Dysregulated production of the iron‐regulatory hormone hepcidin or abnormal interaction with its receptor ferroportin causes a spectrum of iron disorders. We analyzed the critical features of hepcidin and Fpn necessary for their interaction.
Gloria Preza +5 more
openaire +1 more source