Results 101 to 110 of about 17,123 (223)
Детские инфекции (Москва), 2019 Objective: to study the status of markers of the transport system of iron metabolism and the marker profile of HBV infection, depending on the degree of iron overload syndrome in children with chronic hepatitis B.The object of the study were 1 85 ...
F. I. Inoyatova +6 more
doaj +1 more source
Expression of an innate immune element (mouse hepcidin-1) in baculovirus expression system and the comparison of its function with synthetic human hepcidin-25 [PDF]
, 2011 Hepcidin is an innate immune element which decreases the iron absorption from diet and iron releasing from macrophage cell. In contrast to the chemical iron chelators, there has been limited effort applied to the specific use of hepcidin as a new drug ...
Alimohammadian, M. +5 more
core +1 more source
Divalent metal transporter 1 (DMT1) in the brain:implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology [PDF]
, 2015 Iron is required in a variety of essential processes in the body. In this review, we focus on iron transport in the brain and the role of the divalent metal transporter 1 (DMT1) vital for iron uptake in most cells.
Burkhart, Annette +3 more
core +3 more sources
Plant Biology, EarlyView.Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley +1 more source
Rare autosomal dominant hereditary hemochromatosis associated with SLC40A1 gene: ferroportin disease or type 4 hereditary hemochromatosis? [PDF]
, 2019 Ferroportin (FPN1), encoded by the SLC40A1 gene, is the unique cellular iron exporter identified in mammals. FPN1 transfers iron from the intestine and macrophages into the bloodstream. This function is negatively regulated by hepcidin.
Faustino, Paula +7 more
core
Altered iron metabolism is part of the choroid plexus response to peripheral inflammation. [PDF]
, 2009 Iron is essential for normal cellular homeostasis but in excess promotes free radical formation and is detrimental. Therefore, iron metabolism is tightly regulated.
Coppola, Giovanni +7 more
core +1 more source
Parenteral iron—Does it increase infection risk?
Vox Sanguinis, EarlyView.Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb +7 more
wiley +1 more source
Iron deficiency in parkinsonism : region-specific iron dysregulation in Parkinson's disease and multiple system atrophy [PDF]
Alpha synuclein pathology is widespread and found in diverse cell types in multiple system atrophy (MSA) as compared to Parkinson's disease (PD). The reason for this differential distribution is unknown.
Collingwood, Joanna F. +5 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell +3 more
wiley +1 more source