Results 11 to 20 of about 11,138 (199)
FGF10 and the Mystery of Duodenal Atresia in Humans [PDF]
Frontiers in Genetics, 2018 Background: Duodenal atresia (DA) is a congenital obstruction of the duodenum, which affects 1 in 7000 pregnancies and requires major surgery in the 1st days of life. Three morphological DA types are described.
Warwick J. Teague +20 more
doaj +6 more sources
Developmental impairments of craniofacial bone and cartilage in transgenic mice expressing FGF10
Bone Reports, 2023 Mutations in a common extracellular domain of fibroblast growth factor receptor (FGFR)-2 isoforms (type IIIb and IIIc) cause craniosynostosis syndrome and chondrodysplasia syndrome.
Hirotaka Yoshioka +7 more
doaj +2 more sources
Molecular and Cellular Neuroscience, 2008 We used Fgf10-lacZ reporter mice to investigate the distribution and fate of Fgf10-expressing cells in the developing and adult mouse brain. We find that the domain of Fgf10 expression expands post-natally and new niches emerge in the adult brain.
Rice, David +17 more
core +5 more sources
Pbx1 activates Fgf10 in the mesenchyme of developing lungs [PDF]
genesis, 2014 Insufficiency of surfactants is a core factor in respiratory distress syndrome, which causes apnea and neonatal death, particularly in preterm infants. Surfactant proteins are secreted by alveolar type II cells in the lung epithelium, the differentiation
Ching Shang +17 more
core +6 more sources
Differential expression of FGF10 in pancreatic cancer.
, 2023 Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined public and published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most ...
Shahan Mamoor
core +2 more sources
FGF10 and Human Lung Disease Across the Life Spectrum [PDF]
Frontiers in Genetics, 2018 Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease ...
Lawrence S. Prince
doaj +3 more sources
FGF10 and the Mystery of Duodenal Atresia [PDF]
, 2023 The cause of duodenal atresia (DA) is not known. Tandler’s “solid cord” hypothesis conflicts with current biological evidence. In humans, a genetic aetiology is supported by the association with Trisomy 21.
Jones, Matthew Lachlan Markley
core +2 more sources
Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury [PDF]
Frontiers in Genetics, 2018 The lung is morphologically structured into a complex tree-like network with branched airways ending distally in a large number of alveoli for efficient oxygen exchange.
Tingting Yuan +4 more
doaj +2 more sources
A miR-327-FGF10-FGFR2-mediated autocrine signaling mechanism controls white fat browning. [PDF]
, 2017 Understanding the molecular mechanisms regulating beige adipocyte formation may lead to the development of new therapies to combat obesity. Here, we report a miRNA-based autocrine regulatory pathway that controls differentiation of preadipocytes into ...
S. Oyadomari (7774913) +18 more
core +5 more sources
Biology, 2022 For heart regeneration purposes, embryonic stem cell (ES)-based strategies have been developed to induce the proliferation of cardiac progenitor cells towards cardiomyocytes.
Farhad Khosravi +3 more
doaj +1 more source