Results 21 to 30 of about 11,138 (199)
PLoS ONE, 2021 PurposeThe role of fibroblast growth factor (FGF) in orbital fibroblasts (OFs) is rarely known. In this study, we investigated the effect of FGF10 on fibrosis and the inflammation mechanism of Graves' orbitopathy (GO).MethodsOrbital tissue from GO (n ...
Sun Young Jang +4 more
doaj +1 more source
Cell Reports, 2021 Summary: Evidence regarding intraductal papillary neoplasm of the bile duct (IPNB) as a type of precancerous lesion of cholangiocarcinoma is limited. Moreover, a reproducible in vivo model is lacking, and IPNB pathogenesis remains unclear. Here, we use a
Hiroyuki Tomita +19 more
doaj +1 more source
Expression and Clinical Significance of Novel Long Noncoding RNA Fibroblast Growth Factor 10AS and FGF10 in Colorectal Cancer [PDF]
Cell Journal, 2021 Objective: Colorectal cancer (CRC) imposes great health burdens worldwide. Growth factors contribute to cell growth, differentiation, angiogenesis and, most importantly, tumour formation in many types of cancers.
Leili Rejali +4 more
doaj +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
FGF10 and FGF13 genetic variation and tooth-size discrepancies [PDF]
The Angle Orthodontist, 2021 ABSTRACT Objectives To explore whether variations in odontogenesis-related genes are associated with tooth-size discrepancies. Materials and Methods Measurements of the width of permanent teeth ...
Guido Artemio, Marañón-Vásquez +9 more
openaire +2 more sources
Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. [PDF]
PLoS ONE, 2012 The signaling pathways that are essential for gastric organogenesis have been studied in some detail; however, those that regulate the maintenance of the gastric epithelium during adult homeostasis remain unclear.
Allison L Speer +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 The pinna (or auricle) is part of the external ear, acting to capture and funnel sound toward the middle ear. The pinna is defective in a number of craniofacial syndromes, including Lacrimo-auriculo-dento-digital (LADD) syndrome, which is caused by ...
Yang Zhang +6 more
doaj +1 more source
A postnatal progenitor cell population in the mouse cerebral cortex negatively regulated by Fgf10 [PDF]
, 2019 There is growing evidence that neurogenesis is widespread within the postnatal/adult brain, in areas overlapping with expression of Fibroblast growth factor 10 (Fgf10) which is postulated as consistent with neural progenitor cell identity.
Felstead, Hannah
core +3 more sources
Down-regulation of FGF10 in hypospadias prepuce
, 2022 Abstract Background: Fibroblast growth factors (FGF) expressed in the genital tubercle, especially FGF8 and FGF10, may be implicated in the morphogenesis of external genitalia. We investigated the expression of FGF8 and FGF10 in hypospadias prepuce to confirm any correlation.Methods: Hypospadias was classified according to the location of the ...
Susumu Yamada +5 more
openaire +1 more source
Publisher Correction: Fgf10 is essential for limb and lung formation [PDF]
Nature Genetics, 2019 In the version of the paper initially published, Fig. 5a was inadvertently duplicated and presented as both Fig. 5a and 5f, and the correct image for Fig. 5f was omitted. Images of the original and corrected figure panels are shown in the correction notice.
Keisuke, Sekine +10 more
openaire +2 more sources