Results 121 to 130 of about 32,832 (202)

Research on Targeted Therapy for Malignant Tumors of the Biliary Tract. [PDF]

Onco Targets Ther
Yang Y, Zhong H, Zhang J, Wang P.
europepmc   +1 more source

FGFR Gene Rearrangement [PDF]

, 2020
openaire   +1 more source

Recurrent Resistance Mutations to Lirafugratinib Inform Treatment Sequencing in FGFR2-Driven Tumors. [PDF]

Clin Cancer Res
Facchinetti F, Hollebecque A, Barbé R, Jang DM, Alonso-De-Castro B, Brayé F, Bigot L, Nobre C, Da Silva A, Méteau M, Delavigne M, Soares M, Italiano A, Rodriguez J, Mosele F, Beshiri K, Ducreux M, Boilève A, Nikolaev S, Alonso-Garcia I, Vasseur D, Smolenschi C, Bourien H, Cotteret S, Samaniego J, Bernard E, Nicotra C, Ngo-Camus M, Nakazawa S, Tselikas L, Badoual C, André F, Eck MJ, Olaussen KA, Loriot Y, Friboulet L.   +35 more
europepmc   +1 more source

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

FGFR1 and FGFR2 are amplified in many tumor types, yet what determines response to FGFR inhibition in amplified cancers is unknown. In a translational clinical trial, we show that gastric cancers with high-level clonal FGFR2 amplification have a high ...
Chua S, Ajaz M, Herrera-Abreu MT, Gillbanks A, Cunningham D, Kilgour E, Thomas A, Rooney C, Brown G, Babina IS, Cutts R, Johnston SRD, Fenwick K, Sumpter K, Turner NC, Tarazona N, Geh C, Smyth E, Swain A, Chau I, Popat S, Smith NR, Watkins D, Pearson A, Ning J, Campbell J, Peckitt C   +26 more
core  

Fibroblast Growth Factor Receptor (FGFR) Inhibitors for the Treatment of Cholangiocarcinoma: Key Therapeutic Developments and Knowledge Gaps. [PDF]

Drug Des Devel Ther
Erul E, Cifuentes-Canaval S, Santhosh A, Sokolović E, Della Mura M, Cazzato G, Kubilay Tolunay P, Rizzo A.   +7 more
europepmc   +1 more source

Clinical and Genetic Landscape of Glioblastoma, IDH-Wildtype With FGFR Gene Family Alterations. [PDF]

Cancer Sci
Kegoya Y, Otani Y, Mizuta R, Ikemachi R, Kamiura M, Ishida J, Toyooka S, Ennishi D, Tomida S, Tanaka S.   +9 more
europepmc   +1 more source

FGFR Gene Amplification [PDF]

, 2020
openaire   +1 more source

Design and synthesis of an erdafitinib-based selective FGFR2 degrader. [PDF]

Beilstein J Org Chem
Jin Y, Wang S, Pan S, Huang S, Zhou W, Huang X, Zheng L, Chen L.   +7 more
europepmc   +1 more source

FGFR Gene Translocation [PDF]

, 2020
openaire   +1 more source

From blunt tools to bullseyes: The impact of targeted therapy in pediatric neuro-oncology. [PDF]

Neurooncol Adv
Bennett J, Bouffet E.
europepmc   +1 more source