Results 131 to 140 of about 35,836 (258)
International Journal of Cancer, Volume 159, Issue 10, Page 2562-2574, 15 November 2026.While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva +25 more
wiley +1 more source
, 2000 Molecular Cell, 6, 743-750Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Mohammadi, Moosa +7 more
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Cancer Medicine, Volume 15, Issue 11, November 2026.This study applied RNA‐based next‐generation sequencing to one of the largest cohorts of pulmonary carcinoid tumors analyzed to date and revealed rare yet potentially actionable gene rearrangements and variants, including alterations in ALK, BRAF, and EGFR.
Jenni Niinimäki +4 more
wiley +1 more source
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
MedComm, Volume 7, Issue 11, November 2026.Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
, 2016 Clinical activity of FGFR inhibitor AZD4547 in FGFR amplified breast and gastric cancer.
Ros Cutts (15010148) +26 more
core +1 more source
Liquid Biopsy: Past, Present, and Future
MedComm, Volume 7, Issue 11, November 2026.Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu +8 more
wiley +1 more source
MedComm, Volume 7, Issue 11, November 2026.This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
Efficacy and Safety of Lucitanib in Advanced Thymic Carcinoma: A Randomized Phase II Trial
MedComm, Volume 7, Issue 11, November 2026.In this randomized phase II trial, 68 patients with advanced thymic carcinoma after chemotherapy received lucitanib (n = 46) or placebo (n = 22). Median PFS was 5.8 versus 3.7 months by IRC (HR: 0.60; p = 0.105) and 6.6 versus 1.9 months by investigators (HR: 0.53; p = 0.031). Hypertension was the most common grade 3 TRAE (50%).
Wentao Fang +21 more
wiley +1 more source
Oncology and TherapyFibroblast growth factor receptor ( FGFR ) 2 rearrangements define a distinct molecular subset of intrahepatic cholangiocarcinoma (iCCA) with therapeutic potential using FGFR inhibitors.
Hideki Sasanuma, Hironori Yamaguchi
doaj +1 more source
Aging Cell, Volume 25, Issue 11, November 2026.FGF13 is significantly downregulated in the aging brain, particularly in cortical astrocytes within the medial prefrontal cortex. Genetic knockdown of FGF13 in astrocytes accelerates aging phenotypes and impairs neurological function in mice, while its overexpression effectively delays cognitive decline.
Rui Zheng +9 more
wiley +1 more source