Results 151 to 160 of about 34,994 (236)

Discovery of a covalent FGFR2-selective inhibitor overcoming clinically-acquired resistance mutations. [PDF]

Nat Commun
Huang X, Cao X, Zheng L, Luo R, Fang Z, Liang Y, Zhu Y, Chen S, Zheng L, Xu Z, Li X, Liang G, Chen L.   +12 more
europepmc   +1 more source

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

FGFR1 and FGFR2 are amplified in many tumor types, yet what determines response to FGFR inhibition in amplified cancers is unknown. In a translational clinical trial, we show that gastric cancers with high-level clonal FGFR2 amplification have a high ...
Chua S, Ajaz M, Herrera-Abreu MT, Gillbanks A, Cunningham D, Kilgour E, Thomas A, Rooney C, Brown G, Babina IS, Cutts R, Johnston SRD, Fenwick K, Sumpter K, Turner NC, Tarazona N, Geh C, Smyth E, Swain A, Chau I, Popat S, Smith NR, Watkins D, Pearson A, Ning J, Campbell J, Peckitt C   +26 more
core   +1 more source

A subset of high-grade sarcomas with myogenic differentiation are associated with recurrent FGFR fusions. [PDF]

J Pathol Clin Res
Yeung MC, Saoud C, Chiang S, Hameed M, Antonescu CR.   +4 more
europepmc   +1 more source

A Unique WHSC1L1-FGFR1 Fusion in Follicular Dendritic Cell Sarcoma. [PDF]

Pathol Int
Farrajota Neves da Silva P, Haglund de Flon F, Mercke C, Rassidakis GZ.   +3 more
europepmc   +1 more source

FGFR in disease

Reactome - a curated knowledgebase of biological pathways, 2012
openaire   +1 more source

Microenvironment of Sarcomas Associated and Not Associated with Inoculation Sites in Domestic Cats: The Role of Metalloproteinases and Angiogenic Factors. [PDF]

Biology (Basel)
Wright C, Scarano AC, Verdes JM, Scenna SG, Duchene AG, Osacar JM, Di Pierro LM, Risso P, Badura E, Barbeito CG, Acuña F, Santelices Iglesias OA.   +11 more
europepmc   +1 more source

FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review). [PDF]

Int J Mol Med
Qian C, Zhang Z, Wu X, Ti H, Wu J, Yuan Z, Li X, Yuan FL.   +7 more
europepmc   +1 more source

Erdafitinib in Patients With Advanced Solid Tumors With <i>FGFR</i> Alterations (RAGNAR): Results of Tumor-Specific Analyses and Secondary Cohorts. [PDF]

JCO Precis Oncol
Carranza O, Pant S, Schuler M, Witt O, Geoerger B, Loriot Y, Farouk Sait S, Arnold D, Dal Molin GZ, Lugowska I, Winter H, Baldini C, Corassa M, Thomas S, Crow L, Xia Y, Triantos S, Sweiti H, Reardon DA.   +18 more
europepmc   +1 more source

<i>Codonopsis pilosula</i> Lipophilic Extract-Loaded Thermosensitive Nanogel Attenuates Skin Photoaging by Inhibiting the FGFR/PI3K/AKT/mTOR Pathway. [PDF]

Pharmaceutics
Zhou J, Ge Y, Li R, Cheng Z, Gao J, Zheng B.   +5 more
europepmc   +1 more source

Dual targeting of PI3K and FGFR or CDK4/6 reveals synergistic responses in HPV-positive and HPV-negative oropharyngeal cancer spheroids. [PDF]

Mol Ther Oncol
Birgersson M, Lukoseviciute M, Kostopoulou ON, Dalianis T.   +3 more
europepmc   +1 more source